Results 181 to 190 of about 8,264,393 (332)

Referee report. For: A protocol for a systematic review investigating the factors influencing the statistical planning, design, conduct, analysis and reporting of clinical trials [version 1; peer review: 2 approved]

, 2020
Basil Elnazir, Nadeem Gadelseyed
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Research on the deformation mechanisms of red-bed deposits with straight line deposit-bedrock interfaces in Xiangjiaba Reservoir area. [PDF]

Sci Rep
Xiong Y, Dai F, Qi Y, Li S.
europepmc   +1 more source

Statistical analysis of lake sediment geochemical data for understanding surface geological factors and processes: An example from Amazonian upland lakes, Brazil

, 2018
Prafulla Kumar Sahoo, José Tasso Felix Guimarães, Pedro Walfir Martins e Souza Filho, Michael Powell, Marcio Sousa da Silva, Aline Mamede Moraes, Ronnie Alves, Alessandro Sabá Leite, Wilson Nascimento Júnior, Tarcísio Magevski Rodrigues, Vladimir Eliodoro Costa, Roberto Dall’Agnol   +11 more
openalex   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Validation of the Malay Version of the Caregiver Quality of Life Index-Cancer (MCQoL) among caregivers of cancer patients in Malaysia. [PDF]

PLoS One
Ali A, Lim HL, Puslan RZ, Razali NH, Lim CS.   +4 more
europepmc   +1 more source

THE STATISTICAL ANALYSIS OF FACTORS AFFECTING THE SATISFACTION OF DUMLUPINAR UNIVERSITY’S STUDENTS

, 2016
Ergin Uzgören, Mediha Mine Çelikkol, Halime Gürdal, Bahar Çelik   +3 more
openalex   +1 more source

Exploratory Factor Analysis: A Five-Step Guide for Novices

, 2010
B. Williams, A. Onsman, T. Brown
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Expression Characteristics of PAX7 and Its Prognostic Correlation in Breast Cancer. [PDF]

Breast J
Silafu B, Huang J, Aizezi X.
europepmc   +1 more source