Results 251 to 260 of about 3,331,434 (294)

Development and validation of the student readiness and anxiety scale for AI-assisted biology teaching (SRAS-AIBT). [PDF]

Sci Rep
Kadirhanoğulları MK, Özay Köse E.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Incontinence Quiz (IQ): Translation, Cross-Cultural Adaptation, and Psychometric Validation of the French Version. [PDF]

Healthcare (Basel)
Ribeiro A, Sousa J, Neves J, Macedo C, Lumini J.   +4 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Symptom clusters in ME/CFS reflect distinct neuroimmune and autonomic pathophysiological mechanisms: a translational model. [PDF]

J Transl Med
Habermann-Horstmeier L, Horstmeier LM.
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

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Statistical Inference of Minimum Rank Factor Analysis

Psychometrika, 2002
For any given number of factors, Minimum Rank Factor Analysis yields optimal communalities for an observed covariance matrix in the sense that the unexplained common variance with that number of factors is minimized, subject to the constraint that both the diagonal matrix of unique variances and the observed covariance matrix minus that diagonal matrix
Shapiro, A, Ten Berge, JMF
openaire   +3 more sources

On the Statistical Treatment of Residuals in Factor Analysis

Psychometrika, 1962
A method for estimation in factor analysis is presented. The method is based on the assumption that the residual (specific and error) variances are proportional to the reciprocal values of the diagonal elements of the inverted covariance (correlation) matrix. The estimation is performed by a modification of Whittle's least squares technique. The method
openaire   +1 more source

Statistical analysis of nonlinear factor analysis models

British Journal of Mathematical and Statistical Psychology, 1999
This paper presents a Bayesian analysis of a general nonlinear factor analysis model. Both the non‐informative and conjugate prior distributions are considered. A hybrid algorithm that combines the Metropolis‐Hastings algorithm and the Gibbs sampler is implemented to produce direct estimates of the latent factor scores and the structural parameters ...
Hong‐Tu Zhu, Sik‐Yum Lee
openaire   +1 more source