Results 61 to 70 of about 398,172 (288)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Imágenes estadísticas en la cultura visual de la Argentina moderna
Caiana: Revista de Historia del Arte y Cultura Visual, 2014 In Argentina, since the last decades of the nineteenth century, statisticians with diverse backgrounds and varying proximity to the political and intellectual circles of the time generated a growing body of statistical figures from state agencies that ...
Claudia Jorgelina Daniel
doaj
Fast Calculation of the Lomb-Scargle Periodogram Using Graphics Processing Units
, 2010 I introduce a new code for fast calculation of the Lomb-Scargle periodogram, that leverages the computing power of graphics processing units (GPUs). After establishing a background to the newly emergent field of GPU computing, I discuss the code design ...
Aubert +14 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Current Topics in Statistical Graphics
Revista Colombiana de Estadística, 2014 Refereed/Peer ...
openaire +3 more sources
The Complexity of High School Students' Semiotic Graphics in Solving Statistical Problems
Jurnal Multidisiplin IbrahimyThe ability to represent data graphically is a crucial skill in learning statistics, yet it involves complex semiotic processes that are often influenced by students’ cognitive styles.
Ahmad Choirul Anam
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Graphical Methods in Statistics [PDF]
The American Statistician, 1979 Abstract Graphical methods have played a central role in the development of statistical theory and practice. This presentation briefly reviews some of the highlights in the historical development of statistical graphics and gives a simple taxonomy that can be used to characterize the current use of graphical methods.
openaire +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source