Results 141 to 150 of about 3,450,267 (350)

Addressing common inferential mistakes when failing to reject the null-hypothesis [version 2; peer review: 2 approved]

open access: yesF1000Research
Failure to reject a null-hypothesis may lead to erroneous conclusions regarding the absence of an association or inadequate statistical power. Because an estimate (and its variance) can never be exactly zero, traditional statistical tests cannot ...
Amand Schmidt
doaj  

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Addressing common inferential mistakes when failing to reject the null-hypothesis [version 3; peer review: 2 approved]

open access: yesF1000Research
Failure to reject a null-hypothesis may lead to erroneous conclusions regarding the absence of an association or inadequate statistical power. Because an estimate (and its variance) can never be exactly zero, traditional statistical tests cannot ...
Amand Schmidt
doaj  

A Pragmatic Approach to Statistical Testing and Estimation (PASTE)

open access: yesHealth Professions Education, 2018
The p-value has dominated research in education and related fields and a statistically non-significant p-value is quite commonly interpreted as ‘confirming’ the null hypothesis (H0) of ‘equivalence’.
Jimmie Leppink
doaj  

Large Deviation Analysis of Score-Based Hypothesis Testing

open access: yesIEEE Access
Score-based statistical models play an important role in modern machine learning, statistics, and signal processing. For hypothesis testing, a score-based hypothesis test is proposed in Wu et al., (2022).
Enmao Diao   +2 more
doaj   +1 more source

Statistical Analysis based Hypothesis Testing Method in Biological Knowledge Discovery [PDF]

open access: green, 2013
Md. Naseef-Ur-Rahman Chowdhury   +2 more
openalex   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

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