Results 91 to 100 of about 327,556 (313)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Statistical inference from an axiomatic viewpoint

, 2013
The introduction of the axioms of utility led many statisticians to think that there is only one correct statistical inference, that which complies with the results of decision theory.
de Cristofaro, Rodolfo
core   +1 more source

Statistical inference for zero-and-one-inflated poisson models

Statistical Theory and Related Fields, 2017
In this paper, a zero-and-one-inflated Poisson (ZOIP) model is studied. The maximum likelihood estimation and the Bayesian estimation of the model parameters are obtained based on data augmentation method.
Yincai Tang, Wenchen Liu, Ancha Xu
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Statistical inference for inverse problems [PDF]

In this paper we study statistical inference for certain inverse problems. We go beyond mere estimation purposes and review and develop the construction of confidence intervals and confidence bands in some inverse problems, including deconvolution and ...
Bissantz, Nicolai, Holzmann, Hajo
core  

Conservative Statistical Inference

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1977
Summary It is argued that statistical problems can usefully be divided into two classes: one-person problems for which Bayesian techniques are appropriate, and many-person problems, for which Bayesian techniques are not appropriate. Two conditions are presented which it is felt that statistical procedures for many-person problems should ...
openaire   +2 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

The formal relationship between analytic and bootstrap approaches to parametric inference [PDF]

, 2017
Two routes most commonly proposed for accurate inference on a scalar interest parameter in the presence of a (possibly high-dimensional) nuisance parameter are parametric simulation (‘bootstrap’) methods, and analytic procedures based on normal ...
G.A. Young, DiCiccio, TJ, T.A. Kuffner, Young, GA, Kuffner, TA, T.J. DiCiccio   +5 more
core   +1 more source

Some puzzles appearing in statistical inference

Comptes Rendus. Mathématique
Rao-Blackwell theorem is widely known to be a mathematically powerful technique that can be used to improve the precision of an estimator. The procedure entails exploiting a sufficient statistic to obtain an improved estimator or a uniformly minimum ...
Alemam, Seyf, Homei, Hazhir, Nadarajah, Saralees   +2 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source