Results 71 to 80 of about 327,556 (313)

Statistical inference for a multitype epidemic model

open access: yes, 1998
A continuous-time model which allows for k types of susceptible individuals is constructed to study the spread of an infectious disease. Estimation of parameters is considered for the purpose in determining the mechanism of spread and in assessing the ...
Chen, Q   +3 more
core   +1 more source

Statistical Inference Based on L-Moments [PDF]

open access: yesStatistika: Statistics and Economy Journal, 2017
To overcome drawbacks of central moments and comoment matrices usually used to characterize univariate and multivariate distributions, respectively, their generalization, termed L-moments, has been proposed.
Tereza Šimková
doaj  

Geometric statistical inference [PDF]

open access: yesNuclear Physics B, 1999
Finite sample size corrections to the reparametrization-invariant solution of the inverse problem of probability are computed, and shown to converge uniformly to the correct distribution.
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

The renormalization group via statistical inference

open access: yesNew Journal of Physics, 2015
In physics, one attempts to infer the rules governing a system given only the results of imperfect measurements. Hence, microscopic theories may be effectively indistinguishable experimentally.
Cédric Bény, Tobias J Osborne
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Exact statistical inference for categorical data

open access: yes, 2016
Exact Statistical Inference for Categorical Data discusses the way asymptotic approaches have been often used in practice to make statistical inference. This book introduces both conditional and unconditional exact approaches for the data in 2 by 2, or 2
Shan, Guogen, Shan, Guogen,author.
core  

Statistical Inference Using SGD

open access: yesProceedings of the AAAI Conference on Artificial Intelligence, 2018
We present a novel method for frequentist statistical inference in M-estimation problems, based on stochastic gradient descent (SGD) with a fixed step size: we demonstrate that the average of such SGD sequences can be used for statistical inference, after proper scaling.
Tianyang Li   +3 more
openaire   +2 more sources

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