Results 51 to 60 of about 823,510 (266)

Impact of environmental covariates summarization on predictive ability in genomic selection

The Plant Genome
Integrating genomic and environmental information holds the potential for enhancing the predictive power of genomic prediction models when accounting for the genotype‐by‐environment interactions.
Vitor Seiti Sagae, Moysés Nascimento, Ana Carolina Campana Nascimento, Felipe Lopes da Silva, Diego Jarquin   +4 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Image masks of global ship tracks for NASA MODIS data products

Scientific Data
Ship tracks, long thin artificial cloud features formed from the pollutants in ship exhaust, are satellite-observable examples of aerosol-cloud interactions (ACI) that can lead to increased cloud albedo and thus increased solar reflectivity, phenomena of
Pierce Warburton, Kurtis Shuler, Jake P. Zenker, Lekha Patel   +3 more
doaj   +1 more source

Enhancing genomic prediction with Stacking Ensemble Learning in Arabica Coffee

Frontiers in Plant Science
Coffee Breeding programs have traditionally relied on observing plant characteristics over years, a slow and costly process. Genomic selection (GS) offers a DNA-based alternative for faster selection of superior cultivars. Stacking Ensemble Learning (SEL)
Moyses Nascimento, Moyses Nascimento, Ana Carolina Campana Nascimento, Ana Carolina Campana Nascimento, Camila Ferreira Azevedo, Antonio Carlos Baiao de Oliveira, Eveline Teixeira Caixeta, Diego Jarquin   +7 more
doaj   +1 more source

Terahertz tunable optical dual-functional slow light reflector based on gold-graphene metamaterials

New Journal of Physics, 2020
Tunable terahertz optical dual-functional slow light reflector based on gold-graphene metamaterials has been designed and the proposed structure can achieve a good optical reflection effect and slow light effect.
Hui Xu, Zhiquan Chen, Zhihui He, Guozheng Nie, Deqiong Li   +4 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Integrating Environmental Covariates into Adaptability and Stability Analyses: A Structural Equation Modeling Approach for Cotton Breeding

Agriculture
Breeding programs rely on genotype-by-environment interaction (GEI) to recommend cultivars for specific locations. GEI describes how different genotypes perform under varying environmental conditions.
Matheus Massariol Suela, Moysés Nascimento, Ana Carolina Campana Nascimento, Camila Ferreira Azevedo, Paulo Eduardo Teodoro, Francisco José Correia Farias, Luiz Paulo de Carvalho, Diego Jarquin   +7 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Sophisticated Audio Source Separation: A Statistical Exploration of Clarity and Precision With FastICA

Engineering Reports
This study evaluates audio source separation with Fast Independent Component Analysis (FastICA) in a fully specified, reproducible pipeline and benchmarks it against Principal Component Analysis (PCA) and Nonnegative Matrix Factorization (NMF).
Md. Razu Ahmed, Jannatul Mauya, Md. Shamim Reza, Ruhul Amin   +3 more
doaj   +1 more source