Results 51 to 60 of about 9,484,631 (302)

The extension of the largest generalized-eigenvalue based distance metric ) in arbitrary feature spaces to classify composite data points [PDF]

open access: yesGenomics & Informatics, 2019
Analyzing patterns in data points embedded in linear and non-linear feature spaces is considered as one of the common research problems among different research areas, for example: data mining, machine learning, pattern recognition, and multivariate ...
Mosaab Daoud
doaj   +1 more source

Automatic Detection of Cognitive Impairment with Virtual Reality

open access: yesSensors, 2023
Cognitive impairment features in neuropsychiatric conditions and when undiagnosed can have a severe impact on the affected individual’s safety and ability to perform daily tasks.
Farzana A. Mannan   +4 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Stacking Ensemble Learning for Genomic Prediction Under Complex Genetic Architectures

open access: yesAgronomy
Genomic selection (GS) estimates the GEBV from genome-wide markers to reduce generation intervals and optimize germplasm selection, which is particularly advantageous for high-cost or late-expressed traits.
Maurício de Oliveira Celeri   +6 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

A General Formulation of the Kinematic Dipole as a Functional of Selection and Source Properties: Beyond the Ellis–Baldwin Approximation

open access: yesThe Astrophysical Journal Supplement Series
The dipole anisotropy in galaxy and QSO number counts induced by the observer’s motion, known as the kinematic dipole, provides an important test of cosmological isotropy and an independent comparison with the dipole of the cosmic microwave background ...
Tsutomu T. Takeuchi
doaj   +1 more source

Incremental Learning-to-Learn with Statistical Guarantees

open access: yesCoRR, 2018
In learning-to-learn the goal is to infer a learning algorithm that works well on a class of tasks sampled from an unknown meta distribution. In contrast to previous work on batch learning-to-learn, we consider a scenario where tasks are presented sequentially and the algorithm needs to adapt incrementally to improve its performance on future tasks ...
Giulia Denevi   +3 more
openaire   +4 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Assessment of bowel cleansing quality in colon capsule endoscopy using machine learning: a pilot study

open access: yesEndoscopy International Open, 2018
Background and study aims The aim of this study was to develop a machine learning-based model to classify bowel cleansing quality and to test this model in comparison to a pixel analysis model and assessments by four colon capsule endoscopy (CCE) readers.
Maria Magdalena Buijs   +6 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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