Results 291 to 300 of about 329,381 (313)

ShortStop: a machine learning framework for microprotein discovery. [PDF]

BMC Methods
Miller B, de Souza EV, Pai VJ, Kim H, Vaughan JM, Lau CJ, Diedrich JK, Saghatelian A.   +7 more
europepmc   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang, Shengtao Cheng, Huiying Gu, Shan Zhong, Dapeng Zhang, Xin He, Weixian Chen, Haijun Deng, Jihua Ren, Peng Chen, Ming Tan, Hui Zhang, Fan Li, Zhenzhen Zhang, Yuan Hu, Juan Chen   +15 more
wiley   +1 more source

Interpretation of the Transcriptome-Based Signature of Tumor-Initiating Cells, the Core of Cancer Development, and the Construction of a Machine Learning-Based Classifier. [PDF]

Cells
Jeong SH, Kim JJ, Jang JH, Chang YT.
europepmc   +1 more source

A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing

Advanced Science, EarlyView.
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang, Zhengshuo Li, Run Zheng, Xiang Zheng, Jia Wang, Can Liu, Yangge Wu, Yuqing Wen, Chunlin Ou, Songqing Fan, Chenxiao Xu, Junrui Tian, Qun Yan, Hao Nan, Xiaodong Xu, Hui Wang, Qiu Peng, Jian Ma   +17 more
wiley   +1 more source

Artificial Intelligence and Machine Learning in Diabetic Foot Ulcer Care: Advances in Diagnosis, Treatment, Prognosis, and Novel Therapeutic Strategies. [PDF]

J Diabetes Sci Technol
Misir A.
europepmc   +1 more source

Commentary: Static and temporal dynamic changes in brain activity in patients with post-stroke balance dysfunction: a pilot resting state fMRI. [PDF]

Front Neurosci
Wu X, Miao Y.
europepmc   +1 more source

Machine Learning-Driven radiomics on 18 F-FDG PET for glioma diagnosis: a systematic review and meta-analysis. [PDF]

Cancer Imaging
Shahriari A, Ghazanafar Ahari S, Mousavi A, Sadeghi M, Abbasi M, Hosseinpour M, Mir A, Zohouri Zanganeh D, Gharedaghi H, Ezati S, Sareminia A, Seyedi D, Shokouhfar M, Darzi A, Ghaedamini A, Zamani S, Khosravi F, Asadi Anar M.   +17 more
europepmc   +1 more source

A decade of gender bias in machine translation. [PDF]

Patterns (N Y)
Savoldi B, Bastings J, Bentivogli L, Vanmassenhove E.   +3 more
europepmc   +1 more source