Results 81 to 90 of about 521,807 (336)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Machine translation and Welsh: Analysing free statistical machine translation for the professional translation of an under-researched language pair

JoSTrans: The Journal of Specialised Translation, 2017
This article reports on a key-logging study carried out to test the benefits of post-editing Machine Translation (MT) for the professional translator within a hypothetico-deductive framework, contrasting the outcomes of a number of variables which are ...
Ben Screen
doaj   +1 more source

Discriminative Reranking for Grammatical Error Correction with Statistical Machine Translation

North American Chapter of the Association for Computational Linguistics, 2016
Research on grammatical error correction has received considerable attention. For dealing with all types of errors, grammatical error correction methods that employ statistical machine translation (SMT) have been proposed in recent years.
Tomoya Mizumoto, Yuji Matsumoto
semanticscholar   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Non-projective parsing for statistical machine translation [PDF]

Proceedings of the 2009 Conference on Empirical Methods in Natural Language Processing Volume 1 - EMNLP '09, 2009
We describe a novel approach for syntaxbased statistical MT, which builds on a variant of tree adjoining grammar (TAG). Inspired by work in discriminative dependency parsing, the key idea in our approach is to allow highly flexible reordering operations during parsing, in combination with a discriminative model that can condition on rich features of ...
Carreras Perez, Xavier, Collins, Michael
openaire   +4 more sources

Statistical Machine Translation Features with Multitask Tensor Networks

, 2015
We present a three-pronged approach to improving Statistical Machine Translation (SMT), building on recent success in the application of neural networks to SMT.
Devlin, Jacob, Huang, Zhongqiang, Lamar, Thomas, Makhoul, John, Schwartz, Richard, Setiawan, Hendra, Zbib, Rabih   +6 more
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Neural Machine Translation of Spanish-English Food Recipes Using LSTM

JOIV: International Journal on Informatics Visualization, 2022
Nowadays, food is one of the things that has been globalized, and everyone from different parts of the world has been able to cook food from other countries through existing online recipes.
Khen Dedes, Agung Bella Putra Utama, Aji Prasetya Wibawa, Arif Nur Afandi, Anik Nur Handayani, Leonel Hernandez   +5 more
doaj   +1 more source

MATREX: the DCU MT system for WMT 2010 [PDF]

, 2010
This paper describes the DCU machine translation system in the evaluation campaign of the Joint Fifth Workshop on Statistical Machine Translation and Metrics in ACL-2010.
Banerjee, Pratyush, Dandapat, Sandipan, Du, Jinhua, Forcada, Mikel, Haque, Rejwanul, Kumar Naskar, Sudip, Pecina, Pavel, Penkale, Sergio, Srivastava, Ankit Kumar, Way, Andy   +9 more
core  

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source