Results 121 to 130 of about 15,642,380 (303)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Globalising Health Informatics: The Role of GIScience

, 2014
© 2014 European Federation for Medical Informatics and IOS Press. Health systems globally are undergoing significant changes. New systems are emerging in developing countries where there were previously limited healthcare options, existing systems in ...
Nicholas, N, Johnson, J, Robertson, H, Georgiou, A, Travaglia, J   +4 more
core   +1 more source

Using Twitter to investigate opinions about multiple sclerosis treatments: a descriptive, exploratory study [v1; ref status: indexed, http://f1000r.es/4bu]

F1000Research, 2014
Background: Multiple sclerosis (MS) is a common complex disorder, with new treatment options emerging each year. Social media is being increasingly used to investigate opinions about drugs, diseases and procedures.
Sreeram Ramagopalan, Radek Wasiak, Andrew P. Cox   +2 more
doaj   +1 more source

A qualitative study of students’ perspectives on barriers to and challenges in health informatics research in Iran

BMC Health Services Research
Health Informatics (HI) is a crucial field of study that combines computer science, medical science, and information science to develop and produce information systems and software that support healthcare providers.
Hamed Nadri, H. Asadi, Nasim Aslani, A. Garavand   +3 more
semanticscholar   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Public Health and Epidemiology Informatics: Recent Research and Trends in the United States

, 2015
Objectives To survey advances in public health and epidemiology informatics over the past three years. Methods We conducted a review of English-language research works conducted in the domain of public health informatics (PHI), and published in ...
Dixon, Brian E., Kharrazi, H., Lehmann, H. P.   +2 more
core   +1 more source

Electronic health record and genome-wide genetic data in Generation Scotland participants [version 1; referees: 2 approved, 1 approved with reservations]

Wellcome Open Research, 2017
This article provides the first detailed demonstration of the research value of the Electronic Health Record (EHR) linked to research data in Generation Scotland Scottish Family Health Study (GS:SFHS) participants, together with how to access this data ...
Shona M. Kerr, Archie Campbell, Jonathan Marten, Veronique Vitart, Andrew M McIntosh, David J. Porteous, Caroline Hayward   +6 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Implementing digital resources for clinicians' and patients' varying needs. [PDF]

, 2005
This paper presents an overview of several evidence-based medicine and patient information studies conducted across the UK health service over a 4 year period, investigating clinicians', managers', and patients' perceptions of digital resources ...
Blandford, Ann, Blandford, A, Attfield, S, Attfield, Simon, Adams, A, Adams, Anne, Attfield, S., Blandford, A., Adams, A.   +8 more
core   +1 more source

Dietary assessment methods in epidemiological research: current state of the art and future prospects [version 1; referees: 3 approved]

F1000Research, 2017
Self-reported dietary intake is assessed by methods of real-time recording (food diaries and the duplicate portion method) and methods of recall (dietary histories, food frequency questionnaires, and 24-hour dietary recalls).
Androniki Naska, Areti Lagiou, Pagona Lagiou   +2 more
doaj   +1 more source