Results 131 to 140 of about 15,642,380 (303)
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Consumer Health Informatics to Advance Precision Prevention
Yearbook of Medical InformaticsSummary Objective : Consumer health informatics (CHI) has the potential to disrupt traditional but unsustainable break-fix models of healthcare and catalyse precision prevention of chronic disease – a preventable global burden.
Oliver J. Canfell +3 more
semanticscholar +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Global Public Health Informatics Program (GPHIP) [PDF]
In today\ue2\u20ac\u2122s world where diseases spread rapidly without respect for borders, officials rely on technology to deliver accurate information in real time.
core
, 2017 In the summer of 2016 an international group of biomedical and health informatics faculty and graduate students gathered for the 16th meeting of the International Partnership in Health Informatics Education (IPHIE) masterclass at the University of Utah ...
Jaspers, Monique +59 more
core +1 more source
Health Informatics and Mental Health Services: Bridging Gaps in Access, Quality, and Equity
Medicor : Journal of Health Informatics and Health PolicyHealth informatics has emerged as a pivotal tool in transforming mental health services, offering new possibilities for diagnostic precision, treatment planning, and patient engagement.
Hesty Widyasih +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Salary Structures in Health Informatics Academia: A Preliminary Survey Analysis
Applied Clinical InformaticsBackground Health informatics continues to be a continuously evolving discipline. As a result, faculty in health informatics training programs cover a broad range of topics and work in highly diverse academic contexts.
Sue S. Feldman +6 more
semanticscholar +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source