Results 151 to 160 of about 15,642,380 (303)
In this issue of PHINews, the following article highlights the Centers Of Excellence (COE) in Public Health Informatics. CDC began the COE program in 2005 to initiate research for new strategies and tools in Public Health Informatics.
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JMIR DermatologyBackground Chronic dermatologic conditions such as psoriasis, atopic dermatitis, and hidradenitis suppurativa are associated with a high burden of psychiatric comorbidities, including depression, anxiety, and suicidality. Despite growing awareness of the
C. Lamarre +2 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
The Application of Data Mining Techniques in Health Plan Population Management
, 2008 Healthcare has become a data-intensive business. Over the last 30 years, we have seen significant advancements in the areas of health information technology and health informatics as well as healthcare modeling and artificial intelligence techniques ...
Theodore L. Perry +5 more
core +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Exploring the impact of IS theory on health informatics
, 2015 We report the results of a citation analysis of the Health Informatics literature. The study takes the health informatics literature as its starting point, looking inward at the IS literature to seek evidence for the impact of IS theories in healthcare ...
Sophie Cockcroft, Cockcroft, Sophie
core +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
The Application of Data Mining Techniques in Health Plan Population Management
, 2004 Healthcare has become a data-intensive business. Over the last 30 years, we have seen significant advancements in the areas of health information technology and health informatics as well as healthcare modeling and artificial intelligence techniques ...
Theodore L. Perry +5 more
core +1 more source