Results 201 to 210 of about 5,876,781 (310)

A jamming risk warning model for TBM tunnelling based on Bayesian statistical methods. [PDF]

Sci Rep
Wang SJ, Wang LC, Wu LJ, Li X.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Recommendations for a Complete Reporting of Statistical Methods in Veterinary Pharmacology. [PDF]

J Vet Pharmacol Ther
Villarino NF.
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Statistical methods to harmonize electronic health record data across healthcare systems: case study and lessons learned. [PDF]

Bioinformatics
Shi X, Zhai Y, Yu X, Li X, Hazlehurst BL, Nyongesa DB, Sapp DS, Williamson BD, Carrell DS, Healy L, Cushing-Haugen KL, Wong J, Wang SV, Floyd JS, Shattuck K, McGown S, Alam S, Hernández-Muñoz JJ, Li J, Ma Y, Stojanovic D, Raman SR, Davis SE, Cai T, Nelson JC, Heagerty PJ.   +25 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Multivariate Statistical Techniques

This paper serves as an overview of various multivariate statistical techniques that can be used to analyse and describe survey datasets. Such analyses are useful for gaining a better understanding of results and the interpretation thereof. In particular
Pauw, Kalie
core  

Assessment of PlanetScope Spectral Data for Estimation of Peanut Leaf Area Index Using Machine Learning and Statistical Methods. [PDF]

Sensors (Basel)
Ekwe M, Fernando H, James G, Adeluyi O, Verrelst J, Kross A.   +5 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Protocol for a review of statistical methods used to estimate risk ratios and risk differences in parallel cluster randomised trials. [PDF]

Trials
Hall JA, Watson SI, Bishop J, Wang Y, Shaw JF, Taljaard M, Hemming K.   +6 more
europepmc   +1 more source