Results 111 to 120 of about 2,204,741 (325)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Detection of risk factors of acute contrast-induced kidney injury in patients with acute myocardial infarction

open access: yesКлинический разбор в общей медицине
Predictors of the development of contrast-induced acute kidney injury in patients with acute myocardial infarction who underwent coronary angiography and percutaneous coronary intervention have been identified.
Alla A. Ursta   +5 more
doaj   +1 more source

Modelling dynamic portfolio risk using risk drivers of elliptical processes [PDF]

open access: yes
The situation of a limited availability of historical data is frequently encountered in portfolio risk estimation, especially in credit risk estimation.
Schmieder, Christian, Schmidt, Rafael
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Similarity Measures for Clustering SNP and Epidemiological Data [PDF]

open access: yes
The issue of suitable similarity measures for a joint consideration of so called SNP data and epidemiological variables arises from the GENICA (Interdisciplinary Study Group on Gene Environment Interaction and Breast Cancer in Germany) casecontrol study ...
Selinski, Silvia
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Critical Survey on Risk Management in Controlling Administrative Corruption in Relation with Criminological Discourse [PDF]

open access: yesفلسفه حقوق
The aim of the present study is the survey on risk management in controlling administrative corruption in relation with criminological discourse. This study is theoretical and fundamental in terms of its purpose and is descriptive and analytical in ...
Mhadi Mehrpour   +2 more
doaj   +1 more source

PORTFOLIO RISK MANAGEMENT USING THE LORENZ CURVE [PDF]

open access: yes
This paper compiles the risk measures associated with the Lorenz curve. The Lorenz curve is the main tool in economics for measuring income distribution and inequality.
Haim Shalit
core  

Mathematical and Statistical Methods for Actuarial Sciences and Finance

open access: yes, 2010
In actuarial literature the properties of risk measures or insurance premium principles have been extensively studied. We propose a new kind of stop-loss transform and a related order in the multivariate setting and some equivalent conditions.
Corazza, Marco   +3 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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