Results 81 to 90 of about 8,450,169 (300)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Preferential attachment growth model and nonextensive statistical mechanics
, 2004 We introduce a two-dimensional growth model where every new site is located, at a distance $r$ from the barycenter of the pre-existing graph, according to the probability law $1/r^{2+\alpha_G} (\alpha_G \ge 0)$, and is attached to (only) one pre-existing
da Silva, Luciano R. +3 more
core +1 more source
Journal of Taibah University for ScienceExcitation functions for the production route of light non-metallic radioisotopes 11C, 13N, 15O and 18F and metallic radioisotope 64Cu are evaluated using the statistical model code EMPIRE-3.2.
Milan Singh +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Statistical Model Predictions for Pb-Pb Collisions at LHC [PDF]
, 2006 The systematics of Statistical Model parameters extracted from heavy-ion collisions at lower energies are exploited to extrapolate in the LHC regime. Predictions of various particle ratios are presented and particle production in central Pb-Pb collisions
Braun-Munzinger P +10 more
core +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
When your words count: a discriminative model to predict approval of referrals
Journal of Innovation in Health Informatics, 2009 Objective To develop and test a statistical model which correctly predicts the approval of outpatient referrals when reviewed by a specialty service based on nine discriminating variables. Design Retrospective cross-sectional study.
Adol Esquivel +5 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Statistical Model Checking : An Overview
, 2010 Quantitative properties of stochastic systems are usually specified in logics that allow one to compare the measure of executions satisfying certain temporal properties with thresholds.
Delahaye, Benoit, Legay, Axel
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source