Results 111 to 120 of about 30,979,719 (362)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
, 2007 Many statistical models are algebraic in that they are defined in terms of polynomial constraints, or in terms of polynomial or rational parametrizations.
Drton, Mathias, Sullivant, Seth
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Demographic Research, 2006 This paper investigates the effects of birth outcomes on infant mortality for non-Hispanic white, black, and Mexican-American females in the U.S. (1995-1998).
Patricio Solis +4 more
doaj
Leaf area estimation of cassava from linear dimensions
Anais da Academia Brasileira de Ciências, 2017 The objective of this study was to determine predictor models of leaf area of cassava from linear leaf measurements. The experiment was carried out in greenhouse in the municipality of Botucatu, São Paulo state, Brazil.
SAMARA ZANETTI +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
PREDICTIVE STATISTICAL MODELS OF SURFACE MELT WATER RUNOFF ON A SLOPE IN THE AZOV ZONE ROSTOV REGION
Мелиорация и гидротехникаPurpose: to conduct a statistical analysis of the relationship between a number of natural factors and snow evaporation, melt water surface runoff during the snowmelt period on a slope with ordinary chernozem in Rostov region for various agricultural ...
Ivan V. Batishchev +2 more
doaj +1 more source
Statistical Mechanics of Transcription-Factor Binding Site Discovery Using Hidden Markov Models [PDF]
, 2010 Pankaj Mehta +2 more
openalex +1 more source