Results 51 to 60 of about 1,227,299 (287)

Statistical Physics of Fracture Surfaces Morphology

, 2005
Experiments on fracture surface morphologies offer increasing amounts of data that can be analyzed using methods of statistical physics. One finds scaling exponents associated with correlation and structure functions, indicating a rich phenomenology of ...
A. A. Griffith, A. Hansen, A. Hansen, A. Hansen, A.-L. Barabasi, B. B. Mandelbrot, B. Cotterell, B. Davidovitch, B. Davidovitch, B. Davidovitch, B. Skjetne, C. Poirier, Cf. E. Bouchaud, E. Bouchaud, E. Bouchbinder, E. Bouchbinder, E. Bouchbinder, E. Bouchbinder, E. Bouchbinder, E. T. Seppälä, Eran Bouchbinder, F. Anselmet, F. Barra, F. Barra, F. Célarié, F. Reurings, I. Afek, I. Arad, Itamar Procaccia, J. A. Hodgdon, J. Feder, J. Fineberg, J. Kertész, J. Lubliner, J. R. Rice, J. Schmittbuhl, J. Schmittbuhl, J.-J. Ammann, L. Biferale, L. D. Landau, L. I. Salminen, M. B. Hastings, M. L. Falk, R. M. McMeeking, S. Santucci, Shani Sela, T. Engøy, T. Halpin-Healy, T. Halpin-Healy, U. Frisch   +49 more
core   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Statistical tests in particle physics

Revista de Investigación de Física
Particle physics emerged as a pioneer discipline in "big science"; experiments are being carried out in accelerators that are increasing in energy and complexity by the collaborations of thousands of physicists from hundreds of institutes in a few dozen ...
Mississippi Valenzuela
doaj   +1 more source

Statistical physics of pairwise probability models

Frontiers in Computational Neuroscience, 2009
Statistical models for describing the probability distribution over the states of biological systems are commonly used for dimensional reduction. Among these models, pairwise models are very attractive in part because they can be fit using a reasonable
Yasser Roudi, Erik Aurell, Erik Aurell, John A Hertz, John A Hertz   +4 more
doaj   +1 more source

Self-Similar Crossover in Statistical Physics

, 2000
An analytical method is advanced for constructing interpolation formulae for complicated problems of statistical mechanics, in which just a few terms of asymptotic expansions are available.
Baker, Baker, Benettin, Blote, Edwards, Fisher, Girardeau, Gluzman, Irving, Lieb, Muthukumar, Muthukumar, Nakamura, Oguchi, S Gluzman, Saff, Selyugin, Simon, Takahashi, Takahashi, Theodorakopoulos, V.I Yukalov, Von Meyenn, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalova, Čizek   +34 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Quantum Statistical Physics - A New Approach

, 2005
The new scheme employed (throughout the thermodynamic phase space), in the statistical thermodynamic investigation of classical systems, is extended to quantum systems.
Beth, Broglia, Ceperley, D.L. Huber, Edgal, Edgal, Edgal, Fabrocini, Hirschfelder, Huang, Kahn, Kleinert, Lakhno, Landau, Lester, Ohnuki, Singh, Sinha, Smirnov, ter Haar, Tsvelik, U.F. Edgal   +21 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Statistical physics, mixtures of distributions, and the EM algorithm [PDF]

, 1994
We show that there are strong relationships between approaches to optmization and learning based on statistical physics or mixtures of experts. In particular, the EM algorithm can be interpreted as converging either to a local maximum of the mixtures ...
Stolorz, Paul, Utans, Joachim, Yuille, Alan L.   +2 more
core