Results 91 to 100 of about 7,216,857 (259)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Power for Service

open access: yes, 1944
Includes the history of the Puget Sound Power and Light Company power plants and ...
Puget Sound Power and Light Company
core  

Report on Statistical Disclosure Limitation Methodology [PDF]

open access: yes
Originally Prepared by Subcommittee on Disclosure Limitation Methodology 1994; Revised by Confidentiality and Data Access Committee 2005The Federal Committee on Statistical Methodology (FCSM) was organized by the Office of Management and Budget (OMB) in ...
United States. Federal Committee on Statistical Methodology
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Statistical Policy Working Paper 6. Report on Statistical Uses of Administrative Records [PDF]

open access: yes
The first portion of this report provides a review of major administrative report files pertaining to individuals and to businesses. Major statistical uses of administrative records are outlined, including: (1) direct use of the records to obtain ...
United States. Federal Committee on Statistical Methodology
core   +1 more source

A Systematic Review on the Evolution of Power Analysis Practices in Psychological Research

open access: yesPsychologica Belgica
Performing hypothesis tests with adequate statistical power is indispensable for psychological research. In response to several large-scale replication projects following the replication crisis, concerns about the root causes of this crisis – such as ...
Lara Vankelecom   +4 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Hypertension in pregnancy and statistical power [PDF]

open access: yesSao Paulo Medical Journal, 1996
Bothdrugshaveabout90percentefficacyinreducingblood pressure, butitisnotknown wichdrugcarriers lessriskofadverseeffectsforthefetus.Suppose thatonepercentoffetaldeathscouldbeattributed toonedrug,andtheotherdrugcould beattributed with0.5percent; thatmeans a50percent lesschance offetal deaths.
openaire   +4 more sources

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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