Results 51 to 60 of about 4,373,909 (285)

Reliable gains? Evidence for substantially underpowered designs in studies of working memory training transfer to fluid intelligence

Frontiers in Psychology, 2015
In recent years, cognitive scientists and commercial interests (e.g., Fit Brains, Lumosity) have focused research attention and financial resources on cognitive tasks, especially working memory tasks, to explore and exploit possible transfer effects to ...
Tim eBogg, Leanne eLasecki
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Afterglow Light Curves and Broken Power Laws: A Statistical Study

, 2006
In gamma-ray burst research it is quite common to fit the afterglow light curves with a broken power law to interpret the data. We apply this method to a computer simulated population of afterglows and find systematic differences between the known model ...
Beuermann K., Einar H. Gudmundsson, Gudlaugur Jóhannesson, Gunnlaugur Björnsson, Wijers R. A. M. J.   +4 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Chasing Unbiased Spectra of the Universe

, 2013
The cosmological power spectrum of the coherent matter flow is measured exploiting an improved prescription for the apparent anisotropic clustering pattern in redshift space.
Kayo, Issha, Nishimichi, Takahiro, Song, Yong-Seon, Taruya, Atsushi   +3 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

SampSizeCal: The platform-independent computational tool for sample sizes in the paradigm of new statistics [PDF]

Network Biology
Dependent upon the statistical significance p-value and statistical power, the sample size estimation is widely used in various experimental sciences.
WenJun Zhang
doaj  

The statistical power to detect cross‐scale interactions at macroscales

Ecosphere, 2016
Macroscale studies of ecological phenomena are increasingly common because stressors such as climate and land‐use change operate at large spatial and temporal scales. Cross‐scale interactions (CSIs), where ecological processes operating at one spatial or
Tyler Wagner, C. Emi Fergus, Craig A. Stow, Kendra S. Cheruvelil, Patricia A. Soranno   +4 more
doaj   +1 more source

Randomisation in a clinical trial: is it feasible in the Ebola crisis? If it is, then which method is suitable?

Southern African Journal of Infectious Diseases, 2016
Randomisation is an integral component of any sensible clinical trial. Randomisation is the only way we can be sure that the patients have been allocated into the treatment arms with as minimum bias as possible, and that the treatment arms are similar ...
Jesca M. Batidzirai
doaj   +1 more source