Results 201 to 210 of about 5,875,188 (336)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Monitoring carbon emissions using deep learning and statistical process control: a strategy for impact assessment of governments' carbon reduction policies. [PDF]

Environ Monit Assess
Ezenkwu CP, Cannon S, Ibeke E.
europepmc   +1 more source

Computer Vision based Object Detection System for Statistical Process Control

, 2019
Akanksha Hinge
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Early Detection of PRRSV Outbreaks in Breeding Herds by Monitoring Productivity and Electronic Sow Feed Data Using Univariate and Multivariate Statistical Process Control Methods. [PDF]

Transbound Emerg Dis
Pedro Mil-Homens M, Jayaraman S, Rupasinghe K, Wang C, Trevisan G, Dórea F, C L Linhares D, Holtkamp D, S Silva G.   +8 more
europepmc   +1 more source

Application of statistical process control for monitoring bulk tank milk somatic cell count of smallholder dairy farms. [PDF]

Vet World, 2020
Punyapornwithaya V, Sansamur C, Singhla T, Vinitchaikul P.   +3 more
europepmc   +1 more source

Evaluation of diagnosis methods in PCA-based Multivariate Statistical Process Control

, 2018
M. Fuentes-García, G. Maciá-Fernández, J. Camacho   +2 more
semanticscholar   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Detecting outliers beyond tolerance limits derived from statistical process control in patient-specific quality assurance. [PDF]

J Appl Clin Med Phys
Tan HQ, Lew KS, Wong YM, Chong WC, Koh CWY, Chua CGA, Yeap PL, Ang KW, Lee JCL, Park SY.   +9 more
europepmc   +1 more source

Statistical process control (SPC) for coordinate measurement machines

, 2000
R.N. Jr. Escher
openalex   +1 more source