Results 101 to 110 of about 15,562,972 (297)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Improved EWMA and CUSUM Charts Under Modified Successive Sampling for Monitoring Process Dispersion

Journal of Statistical Theory and Applications (JSTA)
The Statistical Process Control (SPC) toolkit is extensively utilized to identify variations in processes, with control charts serving as the most efficient and commonly employed instrument for real-time process monitoring.
Tahir Mahmood, Mehvish Hyder, Syed Muhammad Muslim Raza   +2 more
doaj   +1 more source

A New Approach to Multivariate Statistical Process Control and Its Application to Wastewater Treatment Process Monitoring

International Journal of Prognostics and Health Management
This paper presents a new process monitoring and fault diagnosis approach based on a modified Multivariate Statistical Process Control (MSPC) and evaluates its applicability to municipal wastewater treatment process monitoring.
Ryo Namba, Takumi Obara, Yukio Hiraoka
doaj   +1 more source

Special Issue on “Process Monitoring and Fault Diagnosis”

The following Special Issue entitled “Process Monitoring and Fault Diagnosis” aims to explore the latest progress and perspectives on the application of data analytic techniques to enhance stable operation and safety in chemical processes and
Wei Sun, Cheng Ji
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Advancements in Process Control and Monitoring for Enhanced Efficiency and Quality

Proceedings
Introduction: Process control and monitoring are indispensable for ensuring efficiency and quality across diverse industrial applications [...]
Ujban Hussain, Samiksha Sandeep Tammewar, Yashika Bhattad   +2 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Numerical Methods for Computing the Integrated Average Run Length for Statistical Process Monitoring

Mathematics
Process monitoring involves applying control charts to infer whether the process is stable, or in control, at a given time. There are many control charting procedures available for practitioners.
Steven E. Rigdon
doaj   +1 more source