Results 61 to 70 of about 5,852,793 (269)
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman +17 more
wiley +1 more source
The reporting of statistical significance in scientific journals: A reflexion
Scientific journals in most empirical disciplines have regulations about how authors should report the precision of their estimates of model parameters and other model elements.
Jan M. Hoem
doaj
For a proper use of frequentist inferential statistics in public health
As widely noted in the literature and by international bodies such as the American Statistical Association, severe misinterpretations of P-values, confidence intervals, and statistical significance are sadly common in public health.
Alessandro Rovetta +2 more
doaj +1 more source
Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy +5 more
wiley +1 more source
Introduction to the theory of statistics. Введение в теорию стaтистики
This article discusses the history of statistics. Destinations such as mathematical and descriptive. The need for statistics as a science. It describes the three basic values of statistics.
Zh. K. Kupenova +2 more
doaj
Common pitfalls in statistical analysis: Clinical versus statistical significance
In clinical research, study results, which are statistically significant are often interpreted as being clinically important. While statistical significance indicates the reliability of the study results, clinical significance reflects its impact on ...
Priya Ranganathan +2 more
doaj +1 more source
ABSTRACT Background Neuropsychological complications may impair the qualitative prognosis of patients with pediatric brain tumors. However, multifaceted evaluations cannot be conducted in all patients because they are time consuming and burdensome for patients.
Ami Tabata +9 more
wiley +1 more source
Statistical significance of cis-regulatory modules
Background It is becoming increasingly important for researchers to be able to scan through large genomic regions for transcription factor binding sites or clusters of binding sites forming cis-regulatory modules.
Smith Andrew D +2 more
doaj +1 more source
Redefine statistical significance [PDF]
We propose to change the default P-value threshold for statistical significance from 0.05 to 0.005 for claims of new ...
Benjamin, Daniel J., Camerer, Colin
core
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson +20 more
wiley +1 more source

