Results 61 to 70 of about 5,852,793 (269)

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman   +17 more
wiley   +1 more source

The reporting of statistical significance in scientific journals: A reflexion

open access: yesDemographic Research, 2008
Scientific journals in most empirical disciplines have regulations about how authors should report the precision of their estimates of model parameters and other model elements.
Jan M. Hoem
doaj  

For a proper use of frequentist inferential statistics in public health

open access: yesGlobal Epidemiology
As widely noted in the literature and by international bodies such as the American Statistical Association, severe misinterpretations of P-values, confidence intervals, and statistical significance are sadly common in public health.
Alessandro Rovetta   +2 more
doaj   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy   +5 more
wiley   +1 more source

Introduction to the theory of statistics. Введение в теорию стaтистики

open access: yesХабаршысы. Экономика сериясы, 2016
This article discusses the history of statistics. Destinations such as mathematical and descriptive. The need for statistics as a science. It describes the three basic values of statistics.
Zh. K. Kupenova   +2 more
doaj  

Common pitfalls in statistical analysis: Clinical versus statistical significance

open access: yesPerspectives in Clinical Research, 2015
In clinical research, study results, which are statistically significant are often interpreted as being clinically important. While statistical significance indicates the reliability of the study results, clinical significance reflects its impact on ...
Priya Ranganathan   +2 more
doaj   +1 more source

Criterion‐Related Validity of the Neuropsychological Quick Assessment for Screening Cognitive, Motor, and Behavioral Impairments in Patients With Pediatric Brain Tumors: An Observational Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neuropsychological complications may impair the qualitative prognosis of patients with pediatric brain tumors. However, multifaceted evaluations cannot be conducted in all patients because they are time consuming and burdensome for patients.
Ami Tabata   +9 more
wiley   +1 more source

Statistical significance of cis-regulatory modules

open access: yesBMC Bioinformatics, 2007
Background It is becoming increasingly important for researchers to be able to scan through large genomic regions for transcription factor binding sites or clusters of binding sites forming cis-regulatory modules.
Smith Andrew D   +2 more
doaj   +1 more source

Redefine statistical significance [PDF]

open access: yes, 2018
We propose to change the default P-value threshold for statistical significance from 0.05 to 0.005 for claims of new ...
Benjamin, Daniel J., Camerer, Colin
core  

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson   +20 more
wiley   +1 more source

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