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Statistical significance and clinical significance [PDF]
Medicine is evolving faster than ever and the web and communication channels, among other technological improvements, facilitate the capacity for knowledge generation and knowledge diffusion, not only in the field of medicine but also for science in general. The form of knowledge diffusion that is used most is the publication of scientific articles. In
Alessandro Wasum Mariani +1 more
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Knowledge and Attitude Towards the Translation of Medical Research to Clinical Benefit Amongst Researchers in A Tertiary Care Hospital [PDF]
Introduction: One of the primary goals of any biomedical researcher should be practical applicability or the translation of scientific discoveries to clinical care.
S Shanmugapriya +2 more
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Current controversies: Null hypothesis significance testing
Traditional null hypothesis significance testing (NHST) incorporating the critical level of significance of 0.05 has become the cornerstone of decision‐making in health care, and nowhere less so than in obstetric and gynecological research. However, such
Philip M. Sedgwick +3 more
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It is incredibly essential that the current clinicians and researchers remain updated with findings of current biomedical literature for evidence-based medicine.
Hunny Sharma
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Clinical significance of enlarged cardiophrenic lymph nodes by CT in advanced ovarian cancer
AimThis study aims to assess the clinical influence of enlarged cardiophrenic lymph nodes (CPLN) on staging computed tomography (CT) among patients with advanced ovarian cancer.MethodsThis retrospective cohort study included 320 patients with advanced ...
Sisi Song +5 more
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Interpreting "statistical hypothesis testing" results in clinical research
Difference between "Clinical Significance and Statistical Significance" should be kept in mind while interpreting "statistical hypothesis testing" results in clinical research.
Sanjeev B Sarmukaddam
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BackgroundTraumatic Brain Injury (TBI) is one of the leading causes of injury related mortality in the world, with severe cases reaching mortality rates of 30-40%.
João Fonseca +4 more
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Aberrant DNA Methylation in Esophageal Squamous Cell Carcinoma: Biological and Clinical Implications
Almost all cancer cells possess multiple epigenetic abnormalities, which cooperate with genetic alterations to enable the acquisition of cancer hallmarks during tumorigenesis.
Lehang Lin, Xu Cheng, Dong Yin
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Circular RNAs in prostate cancer: Biogenesis,biological functions, and clinical significance
Circular RNAs (circRNAs) are covalently closed RNA molecules that play important regulatory roles in various tumors. Prostate cancer (PCa) is one of the most common malignant tumors in the world, with high morbidity and mortality.
Xiao Liu +11 more
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Statistical significance (p value) is a considerable measure when the manuscripts were reading or interpreting. On the other hand clinical importance, which is important at least as statistical significance, may not consider every time by authors or ...
Selim Kılıc
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