Results 11 to 20 of about 2,866,404 (318)

HMGB1: Functions, inhibitors and clinical significance [PDF]

open access: yes, 2022
Damage-associated molecular patterns (DAMPs), a term also known as alarmins coined by Walter G. Land, Seong, and Matzinger, are endogenous danger molecules that are released from damaged or dying cells and activate the innate immune system by interacting
Taşkın, E.   +2 more
core   +1 more source

IgM monoclonal gammopathies of clinical significance: diagnosis and management [PDF]

open access: yes, 2022
IgM monoclonal gammopathy of undetermined significance is a pre-malignant condition for Waldenström macroglobulinemia and other B-cell malignancies, defined by asymptomatic circulating IgM monoclonal protein below 30 g/L with a lymphoplasmacytic bone ...
Kersten, Marie José   +22 more
core   +1 more source

Interpreting "statistical hypothesis testing" results in clinical research

open access: yesJournal of Ayurveda and Integrative Medicine, 2012
Difference between "Clinical Significance and Statistical Significance" should be kept in mind while interpreting "statistical hypothesis testing" results in clinical research.
Sanjeev B Sarmukaddam
doaj   +1 more source

Clinical significance of long-term psychoanalytic treatment [PDF]

open access: yes, 2009
Contains fulltext : 90480.pdf (Publisher’s version ) (Open Access)The present study evaluated the clinical significance of long-term psychoanalytic treatment in four groups of about 60 patients in different phases of treatment (before ...
Caspar C. Berghout   +5 more
core   +1 more source

Effect size

open access: yesPsychiatry and Behavioral Sciences, 2014
Statistical significance (p value) is a considerable measure when the manuscripts were reading or interpreting. On the other hand clinical importance, which is important at least as statistical significance, may not consider every time by authors or ...
Selim Kılıc
doaj   +1 more source

Targeting FBPase is an emerging novel approach for cancer therapy

open access: yesCancer Cell International, 2018
Cancer is a leading cause of death in both developed and developing countries. Metabolic reprogramming is an emerging hallmark of cancer. Glucose homeostasis is reciprocally controlled by the catabolic glycolysis and anabolic gluconeogenesis pathways ...
Gao-Min Liu, Yao-Ming Zhang
doaj   +1 more source

RETRACTED: The value, diagnostic efficacy and clinical significance of functional magnetic resonance imaging in evaluating the efficacy of neoadjuvant chemotherapy in patients with triple negative breast cancer

open access: yesFrontiers in Oncology, 2023
BackgroundBreast cancer (BC) is a common malignant tumor in female. In recent years, with the change of fertility pattern and lifestyle, the incidence of breast cancer is increasing year by year, seriously endangering the health and life of women. MRI is
Xiaoping He   +3 more
doaj   +1 more source

Definition and Clinical Significance of the Monoclonal Gammopathy of Undetermined Significance–Like Phenotype in Patients With Monoclonal Gammopathies

open access: yes, 2023
PURPOSE The existence of patients with multiple myeloma (MM) and light-chain (AL) amyloidosis who present with a monoclonal gammopathy of undetermined significance (MGUS)–like phenotype has been hypothesized, but methods to identify this subgroup are not
Paolo Milani   +85 more
core   +1 more source

Interpreting P Values in 2023

open access: yesJournal of Patient-Centered Research and Reviews, 2023
If recent experiences shared among the biostatistician community are indicative of a sea change in research, then a most-welcome culture shift in dialogue surrounding the proper use and interpretation of the P value, which measures statistical ...
Jennifer K. Homa-Bonell
doaj   +1 more source

Pharmaceutical development of an amorphous solid dispersion formulation of elacridar hydrochloride for proof-of-concept clinical studies [PDF]

open access: yes, 2017
Objective: A novel tablet formulation containing an amorphous solid dispersion (ASD) of elacridar hydrochloride was developed with the purpose to resolve the drug’s low solubility in water and to conduct proof-of-concept clinical studies.
Schellens, J. H M   +5 more
core   +1 more source

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