Results 11 to 20 of about 9,750,898 (317)

HMGB1: Functions, inhibitors and clinical significance [PDF]

, 2022
Damage-associated molecular patterns (DAMPs), a term also known as alarmins coined by Walter G. Land, Seong, and Matzinger, are endogenous danger molecules that are released from damaged or dying cells and activate the innate immune system by interacting
Taşkın, E., Kaya, Salih Tunç, Güven, Celal   +2 more
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IgM monoclonal gammopathies of clinical significance: diagnosis and management [PDF]

, 2022
IgM monoclonal gammopathy of undetermined significance is a pre-malignant condition for Waldenström macroglobulinemia and other B-cell malignancies, defined by asymptomatic circulating IgM monoclonal protein below 30 g/L with a lymphoplasmacytic bone ...
Kersten, Marie José, Shirley D’Sa, Ashutosh Wechalekar, D’Sa, Shirley, Vos, Josephine M, Monique C. Minnema, Khwaja, Jahanzaib, D'Sa, Shirley, Marie José Kersten, Josephine M. Vos, Vos, Josephine M., Jahanzaib Khwaja, Khwaja, J, Minnema, Monique C, Wechalekar, A, Minnema, Monique C., Wechalekar, Ashutosh, Minnema, MC, Vos, Josephine M.I., Kersten, MJ, Vos, JM, D'Sa, S, Vos, Josephine M. I.   +22 more
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Clinical significance of long-term psychoanalytic treatment [PDF]

, 2009
Contains fulltext : 90480.pdf (Publisher’s version ) (Open Access)The present study evaluated the clinical significance of long-term psychoanalytic treatment in four groups of about 60 patients in different phases of treatment (before ...
Caspar C. Berghout, Berghout, Caspar C, Zevalkink, D.J., Zevalkink, D.J.; id_orcid, Jolien Zevalkink, Berghout, C.C.   +5 more
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Hypothesis of Genetic Diversity Selection in the Occurrence and Development of 
Lung Cancer: Molecular Evolution and Clinical Significance

Chinese Journal of Lung Cancer, 2023
So far, the monoclonal hypothesis of tumor occurrence and development cannot be justified. The genetic diversity selection hypothesis for the occurrence and development of lung cancer links Mendelian genetics with Darwin's theory of evolution, suggesting
Baodong LIU
doaj   +1 more source

Clinical significance of proliferation index and E-cadherin expression in colorectal adenocarcinoma [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2021
Introduction/Objective. The aim of this study is to examine the association of E-cadherin expression and high proliferation index (proIDX) with clinical and pathological indicators of colorectal cancer progression. Methods.
Žujović Janko, Vuletić Milena, Stojanović Miroslav, Lazović Ranko, Đorđević Nebojša, Radunović Miodrag, Jančić Snežana, Milošević Velimir   +7 more
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Targeting FBPase is an emerging novel approach for cancer therapy

Cancer Cell International, 2018
Cancer is a leading cause of death in both developed and developing countries. Metabolic reprogramming is an emerging hallmark of cancer. Glucose homeostasis is reciprocally controlled by the catabolic glycolysis and anabolic gluconeogenesis pathways ...
Gao-Min Liu, Yao-Ming Zhang
doaj   +1 more source

Noteworthy prognostic value of phospholipase C delta genes in early stage pancreatic ductal adenocarcinoma patients after pancreaticoduodenectomy and potential molecular mechanisms

Cancer Medicine, 2020
The purpose of this investigation was to explore the prognostic value of phospholipase C delta (PLCD) genes in early stage pancreatic ductal adenocarcinoma (PDAC) and its potential molecular mechanisms.
Xin Zhou, Xiwen Liao, Xiangkun Wang, Ketuan Huang, Chengkun Yang, Tingdong Yu, Chuangye Han, Guangzhi Zhu, Hao Su, Quanfa Han, Zijun Chen, Jianlv Huang, Yizhen Gong, Guotian Ruan, Xinping Ye, Tao Peng   +15 more
doaj   +1 more source

Atrial septal aneurysm: Evolution of diagnostic and clinical judgements [PDF]

Терапевтический архив, 2017
The article discusses anatomical and clinical judgements on atrial septal aneurysm (ASA) as a primary cardiac structural abnormality. It presents current approaches to the classification of ASA and its echocardiographic diagnosis.
A S Rudoy, A A Bova, T A Nekhaichik
doaj   +1 more source

The Clinical Significance of Bactermia [PDF]

The Laryngoscope, 1914
n ...
openaire   +2 more sources

Pharmaceutical development of an amorphous solid dispersion formulation of elacridar hydrochloride for proof-of-concept clinical studies [PDF]

, 2017
Objective: A novel tablet formulation containing an amorphous solid dispersion (ASD) of elacridar hydrochloride was developed with the purpose to resolve the drug’s low solubility in water and to conduct proof-of-concept clinical studies.
Schellens, J. H M, Nuijen, B., Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Beijnen, J. H., Sawicki, E.   +5 more
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