Results 31 to 40 of about 9,750,898 (317)

Polymorphisms and gene expression of Notch4 in pulmonary tuberculosis

Frontiers in Immunology, 2023
BackgroundTuberculosis (TB) is a serious public health problem to human health, but the pathogenesis of TB remains elusive.MethodsTo identify novel candidate genes associated with TB susceptibility, we performed a population-based case control study to ...
Weijun Fang, Weijun Fang, Hua Liu, Hua Liu, Lianhua Qin, Jie Wang, Xiaochen Huang, Sha Pan, Ruijuan Zheng, Ruijuan Zheng   +9 more
doaj   +1 more source

The clinical significance of ferritinuria [PDF]

Blood, 1980
Urinary ferritin levels were measured by a “2-site” immunoradiometric assay in normal volunteers and in patients with various hematologic disorders. The mean urinary ferritin concentration in normal subjects averaged 2.2 microgram/liter, only 3% of the serum ferritin level.
D A, Lipschitz, A, Allegre, J D, Cook
openaire   +3 more sources

What is a biomarker?: From its discovery to clinical application [PDF]

Journal of Medical Biochemistry, 2011
The term biomarker in medicine most often stands for a protein measured in the circulation (blood) whose concentration indicates a normal or a pathological response of the organism, as well as a pharmacological response to the applied therapy.
Majkić-Singh Nada
doaj  

Pharmacokinetic interaction of voriconazole and clarithromycin in Pakistani healthy male volunteers: a single dose, randomized, crossover, open-label study

Frontiers in Pharmacology, 2023
Background: Voriconazole an antifungal drug, has a potential for drug-drug interactions (DDIs) with administered drugs. Clarithromycin is a Cytochromes P450 CYP (3A4 and 2C19) enzyme inhibitor, and voriconazole is a substrate and inhibitor of these two ...
Mehwish Mushtaq, Mehwish Mushtaq, Kshaf Fatima, Aneeqa Ahmad, Osama Mohamed Ibrahim, Osama Mohamed Ibrahim, Muhammad Faheem, Yasar Shah   +7 more
doaj   +1 more source

Implications of Isolated Para-Aortic Lymph Node Metastasis in Endometrial Cancer: A Large-Scale, Multicenter, and Retrospective Study

Frontiers in Medicine, 2021
Objective: To systematically evaluate lymph node metastasis (LNM) patterns in patients with endometrial cancer (EC) who underwent complete surgical staging, which included systematic pelvic and para-aortic lymphadenectomy.Methods: Four thousand and one ...
Wenting Li, Wenting Li, Jie Jiang, Yu Fu, Yu Fu, Yuanming Shen, Chuyao Zhang, Shuzhong Yao, Congjian Xu, Min Xia, Ge Lou, Jihong Liu, Bei Lin, Jianliu Wang, Weidong Zhao, Jieqing Zhang, Wenjun Cheng, Hongyan Guo, Ruixia Guo, Fengxia Xue, Xipeng Wang, Lili Han, Xia Zhao, Xiaomao Li, Ping Zhang, Jianguo Zhao, Jianguo Zhao, Jiezhi Ma, Qin Yao, Xiaohang Yang, Xiaohang Yang, Yingyu Dou, Yingyu Dou, Zizhuo Wang, Zizhuo Wang, Jingbo Liu, Jingbo Liu, Yong Fang, Yong Fang, Kezhen Li, Kezhen Li, Beibei Wang, Beibei Wang, Gang Chen, Gang Chen, Xiaodong Cheng, Chaoyang Sun, Chaoyang Sun, Beihua Kong   +48 more
doaj   +1 more source

The Change of Soluble Programmed Cell Death-Ligand 1 in Glioma Patients Receiving Radiotherapy and Its Impact on Clinical Outcomes

Frontiers in Immunology, 2020
BackgroundThe programmed cell death ligand 1 (PD-L1) plays a key role in glioma development. However, due to the specificity of glioma’s anatomical position, the role of its expression as a tumor biomarker is limited.
Xing-Chen Ding, Xing-Chen Ding, Liang-Liang Wang, Yu-Fang Zhu, Yan-Dong Li, Shu-Lun Nie, Shu-Lun Nie, Jia Yang, Hua Liang, Ralph R. Weichselbaum, Jin-Ming Yu, Man Hu   +11 more
doaj   +1 more source

The Clinical Significance of Mesenteric Lymphocytes in Human Colorectal Cancer

Frontiers in Oncology, 2021
ObjectiveThe mesentery is a potential site of residual tumor in patients with colorectal cancer (CRC). However, the mesenteric immune microenvironment remains unclear. In this study, we investigated the immune landscape of the mesentery, particularly the
Zi-Xin Wu, Zi-Xin Wu, Fei Wang, Fei Wang, Liang Li, Yuan Yao, Jie Long, Qing-Qing Luo, Qing-Qing Luo, Zhi-Bin Zhao, Wang-Lin Li, Wang-Lin Li, Jie Cao, Zhe-Xiong Lian   +13 more
doaj   +1 more source

Clinical significance of MEFV gene variation R202Q

, 2022
Background The aim of this study was to evaluate the phenotypic features and the clinical significance of the R202Q mutation of the MEFV gene. Methods We retrospectively reviewed the medical records of Familial Mediterranean Fever patients with M694V ...
Kocakap, Derya Beyza Sayin, Kandur, Yasar, Alpcan, Aysegul, Tursun, Serkan   +3 more
core   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Research Progress of TXNIP as a Tumor Suppressor Gene Participating in the Metabolic Reprogramming and Oxidative Stress of Cancer Cells in Various Cancers

Frontiers in Oncology, 2020
Thioredoxin-interacting protein (TXNIP) is a thioredoxin-binding protein that can mediate oxidative stress, inhibit cell proliferation, and induce apoptosis by inhibiting the function of the thioredoxin system.
Yiting Chen, Yiting Chen, Jieling Ning, Wenjie Cao, Shuanglian Wang, Tao Du, Jiahui Jiang, Xueping Feng, Bin Zhang   +8 more
doaj   +1 more source