Results 51 to 60 of about 9,750,898 (317)

Treatment Changes Clinical Significance Method: Properties, Calculation Method, Decision Making and Limitations

روانشناسی بالینی و شخصیت, 2014
Statistical significant methods are usually used to evaluate the effectiveness of the psychological treatments however, these methods have a number of inherent limitations.
M.A Asghari Moghaddam, M.R Shairi
doaj  

The tyranny of the P-value: effect size matters

Psychiatry and Clinical Psychopharmacology, 2021
Statistical significance does not necessarily imply clinical significance. A P-value of less than 0.05 does not guarantee that the result will be important. Effect size needs to be calculated in order to appraise clinical relevance.
Leslie Citrome
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

What do we be after? Holy p value (statistical significance) or clinical significance?

Psychiatry and Behavioral Sciences, 2011
Most of the readers decide on results and significance according to the p values which are given in the manuscript when they are reading. In fact, the p value which shows the statistical significance is important if it supports the clinical significance.
Selim Kılıc
doaj  

Prevalence and Clinical Significance of Incidental Findings in Cranial Computed Tomography in Patients with Head Trauma [PDF]

Objective: This study evaluated the prevalence and clinical significance of incidental findings detected on cranial computed tomography in patients admitted to the emergency department (ED) with head trauma.
Halil Altınmaden, Adem Az, Özgür Söğüt   +2 more
core   +1 more source

Clinical significance of serum Protease-Activated Receptor-1 (PAR-1) levels in patients with cutaneous melanoma

, 2021
Background: Protease-Activated Receptor-1 (PAR-1) plays an important role in the pathogenesis of multiple malignancies and its expression strongly also affects the outcomes of cancer patients.
Tas, Faruk, Erturk, Kayhan, Karabulut, Senem, Duranyildiz, Derya, Bilgin, Elif   +4 more
core   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Anti-HIV activity in traditional Chinese medicine: clinical implications of monomeric herbal remedies and compound decoctions

Frontiers in Medicine
With the global spread of human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS), the pursuit of potent treatments has ascended as a paramount concern in global healthcare.
Nannan Zhang, Mengyuan Wang, Mengyuan Wang, Ling Gao, Congying Zhang, Xiaoguang Tang, Xianjun Liu, Chunying Bai   +7 more
doaj   +1 more source

HSE National Centre for Clinical Audit Clinical Audit – A Practical Guide

, 2023
This document replaces the previously published “A Practical Guide to Clinical Audit” (HSE 2013). It forms part of a series of resources being developed to support services and all healthcare professionals to ensure the continuation and development of ...
HSE National Centre for Clinical Audit
core  

Haptoglobin Polymorphism: A Novel Genetic Risk Factor for Celiac Disease Development and Its Clinical Manifestations [PDF]

, 2008
Background: Haptoglobin (Hp) α-chain alleles 1 and 2 account for 3 phenotypes that may influence the course of inflammatory diseases via biologically important differences in their antioxidant, scavenging, and immunomodulatory properties.
G. Veres, Földi, I., I. R. Korponay-Szabo, M. Udvardy, Veres, Gábor, Udvardy, M., Korponay-Szabó, Ilma Rita, Tumpek, J., L. Toth, Mate, I., Toth, L., Gyetvai, A., Szathmari, E., Altorjay, István, Nemes, E., A. Gyetvai, E. Szathmari, Papp, Mária, Dinya, T., Varvolgyi, C., J. Tumpek, T. Dinya, Z. Barta, E. Nemes, I. Mate, J. Harsfalvi, Hársfalvi, Jolán, C. Varvolgyi, I. Foldi, Lakatos, Péter László, Kapitany, A., P. L. Lakatos, M. Papp, A. Kapitany, I. Altorjay, Barta, Zsolt   +35 more
core   +1 more source