Results 51 to 60 of about 2,866,404 (318)

Clinical significance of taurine [PDF]

Amino Acids, 2013
The biosynthesis of the b-amino acid, taurine, from cysteine is a two-step process, involving the oxidation of the sulfhydryl group and the decarboxylation of the amino acid (Stipanuk 2004). Although taurine was considered merely an end-product of cysteine degradation for many years, the detection of damaged retina in taurine deficient cats, convinced ...
Stephen W, Schaffer, Takashi, Ito, Junichi, Azuma   +2 more
openaire   +2 more sources

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Lipocalin 2 as a clinical significance in rheumatoid arthritis [PDF]

, 2017
Aim of the study : In this study, serum lipokalin 2 (LCN-2) levels and its clinical and radiological significance in patients with rheumatoid arthritis was evaluated. Material and methods : The study enrolled 37 patients with RA and 34 healthy controls.
Ahmet K. Poyraz, Affan Denk, Gulkesen, Arif, Tulay Yildirim, Akgol, Gurkan, Kaya, Arzu, Poyraz, Ahmet K., Denk, Affan, Gurkan Akgol, Aydin, Suleyman, Yildirim, Tulay, Arzu Kaya, Suleyman Aydin, Arif Gulkesen   +13 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

The clinical significance of otalqia [PDF]

The Laryngoscope, 1905
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openaire   +2 more sources

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Comparative Evaluation of Serum Separator V-Tube™, VQ-Tube™, and K₂EDTA V-Tube™ with Becton Dickinson Tubes for Chemistry, Immunology, and Hematology Examinations

Diagnostics
Background: Rigorous evaluation of vacuum blood collection tubes is essential to ensure the reliability of laboratory results. Methods: In this study, we compared the serum separator tube V-Tube™ (V-Tube SST), the quick-clotting serum separator tube VQ ...
Takho Kang, Seung Gyu Yun, Myung-Hyun Nam, Yunjung Cho, Minjeong Nam   +4 more
doaj   +1 more source

Clinical vs. statistical significance: considerations for clinical laboratories [Elektronisk resurs]

Amongst the main perspectives when evaluating the results of medical studies are statistical significance (following formal statistical testing) and clinical significance.
Tran, Mai Thi Chi, Greaves, Ronda F.,, Cooke, Brian R.,, Markus, Corey,, Greaves, Ronda F., Tran, Mai Thi Chi,, Zakaria, Rosita,, Loh, Tze Ping, Alp, Hamit Hakan,, Alp, Hamit Hakan, Theodorsson, Elvar, Ho, Chung Shun, Markus, Corey, Loh, Tze Ping,, Theodorsson, Elvar,, Ho, Chung Shun,, Zakaria, Rosita, Cooke, Brian R.   +17 more
core   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Ultrasound criteria of extra-nodal extension in papillary thyroid cancer metastases and its clinical signifcance

Сибирский онкологический журнал
The purpose of the research was to identify ultrasound criteria of extranodal extension (ENE) in metastases of papillary thyroid cancer and to evaluate the clinical significance of ENE.Material and Methods.
V. S. Parshin, P. I. Garbuzov, V. V. Polkin, E. I. Kupriyanova, P. A. Isaev, S. A. Ivanov, A. D. Kaprin   +6 more
doaj   +1 more source