Results 41 to 50 of about 3,197,530 (256)

Why Write Statistical Software? The Case of Robust Statistical Methods

open access: yesJournal of Statistical Software, 2004
Robust statistical methods are designed to work well when classical assumptions, typically normality and/or the lack of outliers, are violated. Almost everyone agrees on the value of robust statistical procedures.
Arnold J. Stromberg
doaj   +3 more sources

Gompertz: A Scilab Program for Estimating Gompertz Curve Using Gauss-Newton Method of Least Squares

open access: yesJournal of Statistical Software, 2006
A computer program for estimating Gompertz curve using Gauss-Newton method of least squares is described in detail. It is based on the estimation technique proposed in Reddy (1985).
Surajit Ghosh Dastidar
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

An Introduction to the Special Volume on

open access: yesJournal of Statistical Software, 2011
This special volume of the Journal of Statistical Software on political methodology includes 14 papers, with wide-ranging software contributions of political scientists to their own field, and more generally to statistical data analysis in the the social
Micah Altman   +3 more
doaj  

QInfer: Statistical inference software for quantum applications [PDF]

open access: yesQuantum, 2017
Characterizing quantum systems through experimental data is critical to applications as diverse as metrology and quantum computing. Analyzing this experimental data in a robust and reproducible manner is made challenging, however, by the lack of readily ...
Christopher Granade   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Graphical User Interfaces for R

open access: yesJournal of Statistical Software, 2012
Since R was first launched, it has managed to gain the support of an ever-increasing percentage of academic and professional statisticians. However, the spread of its use among novice and occasional users of statistics have not progressed at the same ...
Ruben D. Ledesma, Pedro M. Valero-Mora
doaj  

An Empirical Study on Writer Identification and Verification From Intra-Variable Individual Handwriting

open access: yesIEEE Access, 2019
The handwriting of a person may vary substantially with factors, such as mood, time, space, writing speed, writing medium/tool, writing a topic, and so on. It becomes challenging to perform automated writer verification/identification on a particular set
Chandranath Adak   +2 more
doaj   +1 more source

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