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Why Write Statistical Software? The Case of Robust Statistical Methods
Robust statistical methods are designed to work well when classical assumptions, typically normality and/or the lack of outliers, are violated. Almost everyone agrees on the value of robust statistical procedures.
Arnold J. Stromberg
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Gompertz: A Scilab Program for Estimating Gompertz Curve Using Gauss-Newton Method of Least Squares
A computer program for estimating Gompertz curve using Gauss-Newton method of least squares is described in detail. It is based on the estimation technique proposed in Reddy (1985).
Surajit Ghosh Dastidar
doaj
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
An Introduction to the Special Volume on
This special volume of the Journal of Statistical Software on political methodology includes 14 papers, with wide-ranging software contributions of political scientists to their own field, and more generally to statistical data analysis in the the social
Micah Altman +3 more
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QInfer: Statistical inference software for quantum applications [PDF]
Characterizing quantum systems through experimental data is critical to applications as diverse as metrology and quantum computing. Analyzing this experimental data in a robust and reproducible manner is made challenging, however, by the lack of readily ...
Christopher Granade +7 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Graphical User Interfaces for R
Since R was first launched, it has managed to gain the support of an ever-increasing percentage of academic and professional statisticians. However, the spread of its use among novice and occasional users of statistics have not progressed at the same ...
Ruben D. Ledesma, Pedro M. Valero-Mora
doaj
The handwriting of a person may vary substantially with factors, such as mood, time, space, writing speed, writing medium/tool, writing a topic, and so on. It becomes challenging to perform automated writer verification/identification on a particular set
Chandranath Adak +2 more
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