Results 231 to 240 of about 8,829,811 (310)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Traduire court, traduire moderne

Revue des Sciences Humaines
Pascale Roux
doaj   +1 more source

Metabolic quiescence of naive-like memory T cells precedes and maintains antigen-specific T cell memory. [PDF]

Nat Immunol
Frischholz S, Schuster EM, Grotz M, Schülein C, Benz J, Kocher K, Klotz L, Varga S, Hiltner T, Alsalameh R, Esse J, Träger J, Held J, Graw F, Pahle J, Spriewald B, Gattinoni L, Buchholz VR, Drost F, Schubert B, Rothenfußer S, Busch DH, Bogdan C, Schober K.   +23 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Measuring representation in clinical trials: Simulations demonstrating how current methods fail in the context of precision medicine. [PDF]

PLoS One
Friedson A, Humphreys A, Cha J.
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Illicit drug supply, naloxone availability, and overdose mortality in the fentanyl era: a systematic review. [PDF]

Health Aff Sch
Khezri M, Holm J, Dahlen A, Johnson C, Agyabeng K, Lei F, Pagán JA, Healton C, Farhat T.   +8 more
europepmc   +1 more source

Key statistics 2006 [PDF]

, 2006

core  

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source