Results 251 to 260 of about 9,557,807 (384)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Generation of nonclassical optomagnonic states under the influences of Stokes scattering process and thermal noise. [PDF]
Ghasemian E, Tavassoly MK.
europepmc +1 more source
Application of Statistics to Problems in Bacteriology
Newell R. Ziegler, H. O. Halvorson
openalex +1 more source
Comparative Statistics on Physical Examinations of Pupils of the Boston Public Schools from December 1, 1915, to March 1, 1920, and Remarks, with Especial Reference to Malnutrition [PDF]
William Devine
openalex +1 more source
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
Causal mediation analysis for time-varying heritable risk factors with Mendelian randomization. [PDF]
Wu Z, Lewis E, Zhao Q, Wang J.
europepmc +1 more source
Health Problems of American Seamen as Measured by Hospital Statistics [PDF]
Robert W. Barclay, Edythe A. Gray
openalex +1 more source
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
Melody: meta-analysis of microbiome association studies for discovering generalizable microbial signatures. [PDF]
Wei Z, Chen G, Tang ZZ.
europepmc +1 more source