Shared genetic architecture between leukocyte telomere length and Alzheimer's disease. [PDF]
Alzheimers Res TherCao Z, Tan Q, Yang H, Xu C.
europepmc +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source
Erratum: Akter E, Hossain AT, Ahamed B, Rahman MH, Hossain AKMT, Barua U, Islam MS, Manna RM, Hossain MA, Ara T, Usmani NG, Chandra P, Ameen S, Jabeen S, Ahmed A, Rahman TZ, Hassan MMU, Islam A, Barr BT, Rahman QS, Arifeen SE, Rahman AE. Excess mortality during COVID-19 and prediction of mortality in Bangladesh: an analysis based on death records in urban graveyards. J Glob Health. 2025;15:04050. [PDF]
J Glob HealthJournal of Global Health Editorial Team.
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Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
Examining factors contributing to mortality in Saudi Arabia: proposing effective healthcare management approaches. [PDF]
BMC Public HealthAljarid S, Alonazi W.
europepmc +1 more source
FEBS Open Bio, EarlyView.20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti +5 more
wiley +1 more source
Statistical and reliability analysis of communication disability severity in Saudi Arabia using novel probability distribution. [PDF]
Sci RepAl-Essa LA +3 more
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FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes
FEBS Open Bio, EarlyView.FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley +1 more source
Characterizing pleiotropy among bipolar disorder, schizophrenia, and major depression: a genome-wide cross-disorder meta-analysis. [PDF]
Psychol MedFriligkou E +6 more
europepmc +1 more source