Quantifying the Measurement Precision of a Commercial Ultrasonic Real-Time Location System for Camera Pose Estimation in Indoor Photogrammetry. [PDF]
Nayko F, Lichti DD.
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
The History of the Lyman-Kutcher-Burman Model and Its Application to the Alpha-Beta Ratio Modeling Using Modern Statistics [PDF]
Yubing Dong +4 more
openalex +1 more source
Predicting extreme thermal degradation of ascorbic acid (Vitamin C) using Bayesian-Inverse Weibull models: Applications in stability analysis and process optimization. [PDF]
Azeem R, Aslam M, Mehmood T, Al-Essa LA.
europepmc +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Gamma exponentiated generalized family of distributions with properties and applications. [PDF]
Alshawarbeh E +3 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Deterministic and highly indistinguishable single photons in the telecom C-band. [PDF]
Hauser N +10 more
europepmc +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
SynVectorDB: embedding-based retrieval system for synthetic biology parts. [PDF]
Li H, Hu J, Song J, Zhou W.
europepmc +1 more source

