Results 31 to 40 of about 851,309 (264)

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

STATSREP-ML: Statistical Evaluation & Reporting Framework for Machine Learning Results [PDF]

open access: yes, 2014
In this report, we present STATSREP-ML, which is an open-source solution for automating the process of evaluating machine-learning results. It calculates qualitative statistics, performs the appropriate tests and reports them in a comprehensive way.
Guckelsberger, Christian, Schulz, Axel
core  

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Machine Learning For In-Region Location Verification In Wireless Networks

open access: yes, 2019
In-region location verification (IRLV) aims at verifying whether a user is inside a region of interest (ROI). In wireless networks, IRLV can exploit the features of the channel between the user and a set of trusted access points. In practice, the channel
Brighente, Alessandro   +3 more
core   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

open access: yesMolecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin   +10 more
wiley   +1 more source

An Algorithmic Theory of Dependent Regularizers, Part 1: Submodular Structure [PDF]

open access: yes, 2013
We present an exploration of the rich theoretical connections between several classes of regularized models, network flows, and recent results in submodular function theory.
Koepke, Hoyt, Meila, Marina
core  

Information-theoretic lower bounds on the oracle complexity of stochastic convex optimization

open access: yes, 2011
Relative to the large literature on upper bounds on complexity of convex optimization, lesser attention has been paid to the fundamental hardness of these problems.
Agarwal, Alekh   +3 more
core   +5 more sources

The Inverse G-Wishart Distribution and Variational Message Passing [PDF]

open access: yes, 2020
Message passing on a factor graph is a powerful paradigm for the coding of approximate inference algorithms for arbitrarily graphical large models. The notion of a factor graph fragment allows for compartmentalization of algebra and computer code.
Maestrini, L., Wand, M. P.
core  

Exploring if Longitudinal Changes on PET Imaging Can Serve as a Biomarker for Stiff Person Syndrome Spectrum Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify metabolic patterns in the brain and musculoskeletal system of stiff person syndrome spectrum disorders (SPSD) patients over time using PET imaging and evaluate the impact of immune therapy on metabolic activity as a surrogate for treatment response.
Munther M. Queisi   +4 more
wiley   +1 more source

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