Results 101 to 110 of about 5,802,672 (263)
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
How many readers understand the discussion on the statistics methodology? A plea for making things reader-friendly. [PDF]
Acta Obstet Gynecol ScandMatsubara S, Ishikawa S.
europepmc +1 more source
Department of Applied Mathematics and Statistics Newsletter, February 2, 2026
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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Department of Applied Mathematics and Statistics Newsletter, October 6, 2025 [PDF]
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Department of Applied Mathematics and Statistics Newsletter, January 12, 2026 [PDF]
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Correction: From clinical records to community care: using real-world evidence in Ayurveda. [PDF]
Front Med (Lausanne)D AS +13 more
europepmc +1 more source
Department of Applied Mathematics and Statistics Newsletter, December 1, 2025
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source