Results 31 to 40 of about 6,999,060 (353)
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
Rejoinder: The Dantzig selector: Statistical estimation when $p$ is much larger than $n$ [PDF]
Rejoinder to ``The Dantzig selector: Statistical estimation when $p$ is much larger than $n$'' [math/0506081]
arxiv +1 more source
Quantile regression with varying coefficients
Quantile regression provides a framework for modeling statistical quantities of interest other than the conditional mean. The regression methodology is well developed for linear models, but less so for nonparametric models.
Kim, Mi-Ok
core +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan+10 more
wiley +1 more source
Statistical Methodology for Pathogen Detection
The main goal of the present study was to discuss the application of the McNemar test to the comparison of proportions in dependent samples. Data were analyzed from studies conducted to verify the suitability of replacing a conventional method with a new one for identifying the presence of Salmonella.
Paulo Rogério Franchin+4 more
openaire +3 more sources
Open statistical issues in particle physics [PDF]
Many statistical issues arise in the analysis of Particle Physics experiments. We give a brief introduction to Particle Physics, before describing the techniques used by Particle Physicists for dealing with statistical problems, and also some of the open statistical questions.
arxiv +1 more source
Gap bootstrap methods for massive data sets with an application to transportation engineering [PDF]
In this paper we describe two bootstrap methods for massive data sets. Naive applications of common resampling methodology are often impractical for massive data sets due to computational burden and due to complex patterns of inhomogeneity.
Appiah, J.+3 more
core +3 more sources
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez+3 more
wiley +1 more source
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang+2 more
wiley +1 more source
Kernel dimension reduction in regression
We present a new methodology for sufficient dimension reduction (SDR). Our methodology derives directly from the formulation of SDR in terms of the conditional independence of the covariate $X$ from the response $Y$, given the projection of $X$ on the ...
Bach, Francis R.+2 more
core +2 more sources