Results 51 to 60 of about 890,957 (263)

New developments in survey data collection methodology for official statistics [PDF]

open access: yes, 2010
There is a growing demand for statistical information in society. National statistical institutes have to satisfy this demand. The way they attempt to accomplish this, changes over time. Changes in survey methodology for official statistics may have been
Bethlehem, J.
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Bayesian Circular Statistics: von Mises-based solutions for practical problems

open access: yes, 2019
Researchers often analyze data that is either numerical, such as height in centimeters, or is divided into categories, such as level of education. However, you can also encounter observed angles, such as wind directions in degrees from north.
Methodology and statistics for the behavioural and social sciences   +3 more
core  

Some Asymptotic Results on Box-Cox Transformation Methodology

open access: yes, 1996
Communications in Statistics - Theory and Methods252403 ...
Yang, Z., YANG, Zhenlin
core   +1 more source

Properties of hypothesis testing techniques and (Bayesian) model selection for exploration-based and theory-based (order-restricted) hypotheses [PDF]

open access: yes, 2015
In this paper, the performance of six types of techniques for comparisons of means is examined. These six emerge from the distinction between the method employed (hypothesis testing, model selection using information criteria, or Bayesian model selection)
Kuiper, Rebecca M.   +3 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Cost-efficient designs for three-arm trials with treatment delivered by health professionals: Sample sizes for a combination of nested and crossed designs

open access: yes, 2018
Background: This article studies the design of trials that compare three treatment conditions that are delivered by two types of health professionals. The one type of health professional delivers one treatment, and the other type delivers two treatments,
Methodology and statistics for the behavioural and social sciences   +3 more
core   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Conceptual issues of research methodology for the behavioural, life and social sciences

open access: yes, 2003
Research methodology (RM) must be clearly separated from substantive fields, such as medicine, psychology, education, sociology and economics, and, on the other side, from the philosophy of science and statistics.
Mellenbergh, G.J.   +7 more
core   +1 more source

Statistical aspects of research methodology

open access: yesJournal of British Surgery, 1991
Abstract Many reports in the medical literature are flawed through poor presentation of numerical results, or, more seriously, by the use of inadequate or inappropriate statistical methodology. This article expands on the more complex methodological issues.
openaire   +2 more sources

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