Results 91 to 100 of about 1,688,539 (296)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

The Viability of Topic Modeling to Identify Participant Motivations for Enrolling in Online Professional Development

open access: yesOnline Learning
Identifying motivation for enrollment in MOOCs has been an important way to predict participant success rates. But themes for motivation have largely centered around themes for enrolling in any MOOC, and not ones specific to the course being studied.  In
Heather Allmond Barker   +3 more
doaj   +1 more source

Mapping the Field of Statistics Education Research in Search of Scholarship

open access: yesInternational Journal for the Scholarship of Teaching and Learning, 2011
This paper is intended as a contribution to the advancement of scholarship in the field of statistics education, which directly links with the scholarship of teaching and learning.
Linda van der Merwe, Annette Wilkinson
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Active-Learning Class Activities and Shiny Applications for Teaching Support Vector Classifiers

open access: yesJournal of Statistics and Data Science Education
Support vector classifiers are one of the most popular linear classification techniques for binary classification. Different from some commonly seen model fitting criteria in statistics, such as the ordinary least squares criterion and the maximum ...
Qing Wang, Xizhen Cai
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Sexuality and the Aging Adult: The Attitude and Practice of Physicians and Nurse Practitioners [PDF]

open access: yes, 2005
Background: As the population ages, many quality of life issues will generate discussion. One such issue is sexuality of the aging adult. While there is substantial documentation related to the physiology and desires of the aging adult, little is known ...
Runsvold, Susan
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

A Topic-Specific Evaluation of Students’ Attitudes Towards Statistics

open access: bronze, 2022
Dorcas Modupe Okewole   +3 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

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