Results 101 to 110 of about 53,712,339 (311)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Navigating through archives, libraries and museums: Topic Maps as a harmonizing instrument [PDF]
, 2005 The paper deals with the possibility of creating a topic map based system where different sectors of cultural heritage would interact with users, by monitoring the navigation histories of users and the statistics on the searches, in order to authorize ...
Vassallo, Salvatore
core +1 more source
National Vital Statistics System Division of Vital Statistics Newsletter ; December 2023 issue
Inside this issue \u2013 Information regarding the 2023 Data Year Close-Out; Collaborating Office of Medical Examiners and Coroners (COMEC) updates; Vital Statistics Modernization Community of Practice information (NVSS COP) and much more\u2026nvss ...
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Methodological approaches to the formation of indicators of state programs of the Russian Federation
Путеводитель предпринимателяThe purpose of the article is to develop analytical approaches and recommendations for adjusting the current system of strategic planning documents indicators developed at the federal level, including in various sectors of statistics, as well as ...
S. V. Brovchak, M. E. Skopintseva
doaj +1 more source
National Vital Statistics System Division of Vital Statistics newsletter ; October 2023
Inside this issue \u2013 Notable publication information on Fetal Mortality in the United States; Vital Statistics Modernization Community of Practice information (NVSS COP) regarding phase III of the jurisdictional outreach effort, and much more ...
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
National Vital Statistics System Division of Vital Statistics newsletter ; July 2022
Inside this issue \u2013 Information regarding the upcoming August 2022 VSCP Director\u2019s Webinar; Vital Statistics Modernization Community of Practice information; and much; Notable publication information on Trends and Characteristics in Gestational
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Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Journal of the Royal Statistical Society Series A: Statistics in Society, 2014 openaire +1 more source