Results 121 to 130 of about 55,852,728 (309)
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
National Vital Statistics System Division of Vital Statistics newsletter ; June 2023
Inside this issue \u2013 Updated information regarding the 2022 data year close-outs for death and fetal death files; Notable publication information on provisional birth data for 2022; Vital Statistics Modernization Community of Practice information and
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Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
National Vital Statistics System Division of Vital Statistics newsletter ; February 2023
Inside this issue \u2013 Information regarding the 2022 data year close-out involving the 2022 birth, death, and fetal death files; Notable publication information on mothers who smoked during pregnancy; Vital Statistics Modernization Community of ...
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Proceedings of the international collaborative effort on injury statistics, Volume 1 [PDF]
Called "Volume I" as it is the proceedings of the first meeting."On May 18-20, 1994 the National Center for Health Statistics (NCHS) convened the first symposium of the International Collaborative Effort (ICE) on Injury Statistics.
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Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
National Vital Statistics System Division of Vital Statistics Newsletter ; November 2020
Inside this issue \u2013 Information about reporting injuries on the death certificate; overview of the vital statistics modernization community of practice; results from new reports about maternal and infant characteristics among women with confirmed or
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Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
National Vital Statistics System Division of Vital Statistics Newsletter ; May 2021
Inside this issue \u2013 Important reminder regarding the 2021 VSCP Annual Meeting; Notable report on Changes in Births to New York City Residents Occurring Outside New York City, by Race and Hispanic Origin of the Mother; Information regarding the Vital
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Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source