Results 171 to 180 of about 2,998,558 (396)

The distribution of the economic activity in the Mediterranean axis. Identification of cluster by sectors of economic activity. [PDF]

open access: yes
Agglomeration economies play an important role in the explanation of the development and regional growth. For this reason, there exists a growing interest in the analysis of standards of co-localisation of the economic activities.
Ana Angulo   +2 more
core  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Tensor Topic Modeling Via HOSVD [PDF]

open access: yesarXiv
By representing documents as mixtures of topics, topic modeling has allowed the successful analysis of datasets across a wide spectrum of applications ranging from ecology to genetics. An important body of recent work has demonstrated the computational and statistical efficiency of probabilistic Latent Semantic Indexing (pLSI)-- a type of topic ...
arxiv  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

Catolici și ortodocși în Moldova: aspecte ideologice și sociale în sate mixte confesional

open access: yesSociologie Românească, 2004
The aim of the article is to investigate the relationships of the Catholic and Orthodox populations living together in two villages from Bacãu County. In any case, the approach does not exhaust the topic. It focuses instead on the matrimonial dimensions.
Stelu Șerban
doaj  

Topic modeling in the stream of short messages in Russian

open access: yesРоссийский технологический журнал
Objectives. This work is devoted to the topic modeling of short messages received through social networks or in another way in the form of a series of short messages.
Elena S. Mozaidze
doaj   +1 more source

Repo Markets - Experiences and opportunities in Hungary [PDF]

open access: yes
More and more questions have arisen recently in the National Bank of Hungary about repo markets. The topic came into the lime light with the latest changes of monetary policy instruments.
Dániel Szakály, Henrik Tóth
core  

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