Results 131 to 140 of about 3,465,070 (364)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Empirical Research in Statistics Education [PDF]
, 2016 A. Eichler, Lucía Zapata‐Cardona
openalex +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
5 essentials for effective evaluation [PDF]
All education programs are well-intentioned and many of them are highly effective. However, there are usually more ways than one to achieve good educational outcomes for students. When faced with this scenario, how do educators and education policymakers
Centre for Education Statistics and Evaluation
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Reparable Harm: Assessing and Addressing Disparities Faced by Boys and Men of Color in California [PDF]
, 2009 The California Endowment commissioned this report to highlight the most glaring inequities in socioeconomics, health, safety, and education faced by African-American and Latino men and boys in the state.
Dana J. Schultz +2 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
From urn models to box models: Making Neyman's (1923) insights accessible
Journal of Causal InferenceNeyman’s 1923 paper introduced the potential outcomes framework and the foundations of randomization-based inference. We discuss the influence of Neyman’s paper on four introductory to intermediate-level textbooks by Berkeley faculty members (Scheffé ...
Lin Winston +3 more
doaj +1 more source
Higher education institutions : subject profile [PDF]
, 2011 "This briefing provides an overview of Higher Education Institutions in Scotland.
Berry, Kate
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