Results 51 to 60 of about 3,420,007 (338)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Changing attitudes and facilitating understanding in the undergraduate statistics classroom: A collaborative learning approach

Journal of the Scholarship of Teaching and Learning, 2013
Collaborative and problem-based learning strategies are theorized to be effective methods for strengthening undergraduate science, technology, engineering, and mathematics education.
Erin M. Curran, Kerri Carlson, Dayius L Turvold Celotta   +2 more
doaj  

Are Statistics Labs Worth the Effort?--Comparison of Introductory Statistics Courses Using Different Teaching Methods

Numeracy, 2010
This paper compares the academic performance of students in three similar elementary statistics courses taught by the same instructor, but with the lab component differing among the three.
Jose H. Guardiola, Nadina Duran-Hutchings, Hassan Elsalloukh   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Statistics educational potential

Izvestiya MGTU MAMI, 2015
Education statistics should reflect the educational potential of the country on various parameters. In modern conditions the total cost of education, professional training is no longer considered as overhead. They are Xia profitable kind of investment. Education creates the potential quantitative and qualitative resources of skilled labor available to ...
openaire   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Assessing Statistical Anxiety Among Online and Traditional Students

Frontiers in Psychology, 2019
The purpose of this study was to determine whether scores on the Statistical Anxiety Scale (SAS) manifest in the same way for students in online and traditional statistics courses.
Marta Frey-Clark, Prathiba Natesan, Monique O’Bryant   +2 more
doaj   +1 more source

Introducing Undergraduates to Concepts of Survey Data Analysis

Journal of Statistics Education, 2020
Increasingly students, particularly those in the social sciences, work with survey data collected through a more complex sampling method than a simple random sample.
Pamela S. Fellers, Shonda Kuiper
doaj   +1 more source

A Study on Student Performance, Engagement, and Experience With Kaggle InClass data Challenges

Journal of Statistics and Data Science Education, 2021
Kaggle is a data modeling competition service, where participants compete to build a model with lower predictive error than other participants. Several years ago they released a simplified service that is ideal for instructors to run competitions in a ...
Julia Polak, Dianne Cook
doaj   +1 more source