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Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Statistical Education and E-Learning
Since the start of the 2002 academic year, the Department of Sciences of Education of the University of Lyon2, in partnership with the University of Rouen and the CNED (Centre National d'Enseignement à Distance ) of Poitiers (France), has put forward a pedagogical plan of action allowing students to prepare a B.SC degree in Sciences of Education.
openaire +2 more sources
The Economic Benefits of Education [PDF]
Provides facts, statistics, a chart, and resources pertaining to the economic outcomes of ...
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
On Simulation and Statistical Education [PDF]
SYNOPTIC ABSTRACTDiscrete event simulation has been nurtured by statistical analysis for many years. The converse is not true. However, recent advances in computer technology and software development have made PC's running specialized simulation languages readily available. This paper discusses how discrete event simulation, implemented via specialized
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
This article examines the integration of cognitive psychology research and technology within existing frameworks of statistics course design and implementation for a sequence of flipped graduate-level courses.
Jason C. Immekus
doaj +1 more source
Exploration on the Industry-education Integration Mode of Statistics Major in Applied Universities [PDF]
Hongmei Li
openalex +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Statistics education is increasingly important to our society with enrolment increases of 16% in introductory statistics courses and 85% in upper-level statistics courses.
Tamarah Smith, Ting Dai
doaj

