Results 81 to 90 of about 3,465,070 (364)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Influence of culture on secondary school students' understanding of statistics: A Fijian perspective [PDF]

open access: yes, 2014
Although we use statistical notions daily in making decisions, research in statistics education has focused mostly on formal statistics. Further, everyday culture may influence informal ideas of statistics.
Sharma, Sashi
core   +1 more source

The Inclusion Lottery: who's in and who's out? Tracking inclusion and exclusion in New South Wales government schools [PDF]

open access: yes, 2011
The last few decades have witnessed a broad international movement towards the development of inclusive schools through targeted special education funding and resourcing policies.
Graham, Linda, Sweller, Naomi
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Survey on the current status of statistical cognition and teaching needs of Chinese medical students

open access: yesFrontiers in Public Health
PurposeTo assess medical students’ needs regarding statistics education and inform potential reforms in medical statistics teaching.MethodA self-administered questionnaire survey was conducted among 274 medical students from five Chinese institutions ...
Hui Ouyang, Siyang Wang, Lingyun Huang
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

A Bayesian Statistics Course for Undergraduates: Bayesian Thinking, Computing, and Research

open access: yesJournal of Statistics Education, 2020
We propose a semester-long Bayesian statistics course for undergraduate students with calculus and probability background. We cultivate students’ Bayesian thinking with Bayesian methods applied to real data problems. We leverage modern Bayesian computing
Jingchen Hu
doaj   +1 more source

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