Results 101 to 110 of about 3,281 (295)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

New method for experimental modal analysis of hydrogenerator's stator core using the excitation from the Poles

open access: yesThe Journal of Engineering, 2019
The study of stator core vibrations generated by electromagnetic forces in electrical machines is of great practical and theoretical interest. An important part of the problem is the correct determination of mode shapes and eigen frequencies of the ...
Allan de Barros   +9 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Stator Structures and Models of Using Grain-Oriented Electrical Steels for High-Power-Density PMSMs

open access: yesMachines
This article studies different stator structures and modeling methods for using grain-oriented electrical steels (GOES) to improve the performance of high-power-density permanent magnet synchronous motors (PMSMs).
Guanglin Li   +4 more
doaj   +1 more source

Linear consequent pole Halbach array flux reversal machine

open access: yesThe Journal of Engineering, 2019
This paper presents a linear variable reluctance permanent magnet (LVRPM) machine where the armature winding and inset Halbach array permanent magnets (PMs) are mounted on E-core stators.
Mohammad Abdul Hakim Raihan   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

FEM approach for diagnosis of induction machines' non-adjacent broken rotor bars by short-time Fourier transform spectrogram

open access: yesThe Journal of Engineering, 2019
Rotor electrical faults are an issue frequently encountered when applying condition monitoring and fault diagnosis on induction machines. The detection via the analysis of the stator current becomes challenging when the rotor cage suffers from multiple ...
Panagiotis A. Panagiotou   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Effect of a Variable Cantilevered Stator on 1.5-Stage Transonic Compressor Performance

open access: yesInternational Journal of Turbomachinery, Propulsion and Power
Future aero engine designs must address environmental challenges and meet noise and emissions regulations. To increase efficiency and reduce size, axial compressors require higher pressure ratios and a more compact design, leading to necessary ...
Benedikt Radermacher   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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