Results 141 to 150 of about 9,602,908 (345)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Effect of combined pressure and temperature distortion orientation on high-bypass-ratio turbofan engine stability [PDF]
Total-temperature, static-pressure and total-pressure distributions were measured in the inlet duct upstream of the engine inlet and within the fan and compressor of a YTF34 turbofan engine.
Mehalic, C. M., Soeder, R. H.
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Analytical and experimental investigation of stator endwall contouring in a small axial-flow turbine. 1: Stator performance [PDF]
Three stator configurations were studied to determine the effect of stator outer endwall contouring on stator performance. One configuration was a cylindrical stator design.
Haas, J. E.
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Computer program for preliminary design and analysis of V/STOL tip-turbine fans [PDF]
Computer program for design and analysis of V/STOL tip turbine ...
Auer, B. M., Haller, H. C., Lieblein, S.
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Noise from turbomachinery [PDF]
A review is made of turbomachinery noise from turbofan engines as typified by fan noise. The mechanisms and theories of fan noise are reviewed and concepts for its reduction, including acoustic suppression are discussed. Correlations of the overall noise
Conrad, E. W., Feiler, C. E.
core +1 more source

