Results 201 to 210 of about 1,727,830 (339)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

The impact of stator module gaps on the performance of canned permanent magnet synchronous motors with segmented stators. [PDF]

Sci Rep
Ming L, Jixin Z, Guanghui D, Shuxian L.
europepmc   +1 more source

The optimistic brain: Trait optimism mediates the influence of resting‐state brain activity and connectivity on anxiety in late adolescence [PDF]

, 2018
Song Wang, Yajun Zhao, Bochao Cheng, Xiuli Wang, Xun Yang, Ching‐Po Lin, Xueling Suo, Qiyong Gong   +7 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Huge transverse Maxwell stress in ferroelectric fluids and prototyping of new ferroelectric motors. [PDF]

Commun Eng
Tsukamoto T, Nishimura S.
europepmc   +1 more source

Synergistic Binding of bHLH Transcription Factors to the Promoter of the Maize NADP-ME Gene Used in C4 Photosynthesis Is Based on an Ancient Code Found in the Ancestral C3 State [PDF]

, 2018
Ana Rita Borba, Tânia S. Serra, Alicja Górska, Paulo Gouveia, André M. Cordeiro, Ivan Reyna‐Llorens, Jana Kneřová, Pedro M. Barros, Isabel A. Abreu, M. Margarida Oliveira, Julian M. Hibberd, Nelson J. M. Saibo   +11 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Insertion of Fluorescent Proteins Near the Plug Domain of MotB Generates Functional Stator Complexes. [PDF]

Microbiologyopen
Gurung JP, Ridone P, Biquet-Bisquert A, Bryant G, Pedaci F, Nord AL, Baker MAB.   +6 more
europepmc   +1 more source

Lyapunov Conditions for Finite-Time Input-to-State Stability of Impulsive Switched Systems [PDF]

Taixiang Zhang, Jinde Cao, Xiaodi Li
openalex   +1 more source

Unraveling Excited-Singlet-State Aromaticity via Vibrational Analysis [PDF]

, 2017
Juwon Oh, Young Mo Sung, Hirotaka Mori, Seongchul Park, Kjell Jorner, Henrik Ottosson, Manho Lim, Atsuhiro Osuka, Dongho Kim   +8 more
openalex   +1 more source