Results 141 to 150 of about 8,442,055 (315)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Status of Women at Iowa State University 2014

open access: yes, 2019
This report documents the representation and experiences of women at the Iowa State University using statistical data and responses to several surveys of students, staff, and faculty.
Status of Women Subcommittee of the University Committee on Women
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Facts about the status of women in Connecticut's prison /

open access: yes, 2006
Updated Feb. 2006; Title from cover.; " ... with information supplied by the CT Department of Correction, December 2005."; Harvested from the web on 12/14 ...
Homola, Christa M.
core  

Терапия нарушений произношения в свете интеграции знаний современной фонетики и логопедии : феномен ротацизма как объект исследования

open access: yesLangues & Cultures
Цель данного исследования — осветить феномен речевых нарушений, возникающих вследствие дефектов или отклонений в артикуляции. Подобные нарушения могут вызывать у страдающих этим расстройством чувство стеснения и неудобства, нередко приводящее к ...
Houaria ELHADJ ALI
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Submission to the Ontario Legislature's Committee on revision of the Employment Standards Act

open access: yes
The Ontario Committee on the Status of Women, a grassroots feminist group, was established in 1970. Its purpose was to seek implementation in Ontario of the Recommendations of the Royal Commission on the Status of ...
Ontario Committee on the Status of Women
core  

Where Connecticut stands

open access: yes, 2007
"Prepared for the Permanent Commission on the Status of Women, Connecticut General Assembly"--Cover.; "June 2007."; Harvested from the web on 5/16 ...
Pearce, Diana.
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Brief to Ontario Attorney-General

open access: yes
The Ontario Committee on the Status of Women, a grassroots feminist group, was established in 1970. Its purpose was to seek implementation in Ontario of the Recommendations of the Royal Commission on the Status of ...
Ontario Committee on the Status of Women
core  

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