Results 221 to 230 of about 14,914,334 (297)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

The impact of subjective socioeconomic status and threat cues on intertemporal decision-making. [PDF]

Front Psychol
Zeng Z, Chen Y, Qu W.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Anthracycline-Free Neoadjuvant Pertuzumab-Trastuzumab-Taxane in Patients with HER2-Positive Early Breast Cancer: Hormone Receptor Status as a Key Determinant of Pathological Complete Response. [PDF]

Biomedicines
Irelli A, Sidoni T, Pavese F, Rotondaro S, Luzi C, Zelli V, Centonze S, Patruno LV, Zazzeroni F, Tessitore A, Cannita K.   +10 more
europepmc   +1 more source

Association between socioeconomic status and cardiovascular disease by sex: Mediating roles of psychological and behavioral factors. [PDF]

PLoS One
Choi J, Cho SI.
europepmc   +1 more source

The association between systemic immune-inflammation index and periodontitis in adults with and without hyperlipidemia: a population-based study. [PDF]

BDJ Open
Xie Y, Zhou S.
europepmc   +1 more source

Oral Health Status as a Mediating Effect Between Psychosocial Factors and Oral Health-Related Quality of Life. [PDF]

Int Dent J
Jiang L, Loschke N, Ziebolz D, Reissmann DR, Schmalz G.   +4 more
europepmc   +1 more source

Perceived organizational status and change-oriented organizational citizenship behavior: mediating role of psychological empowerment and moderating role of organizational error tolerance. [PDF]

BMC Psychol
Zhang B, Li Z, Lin M, Liu M.
europepmc   +1 more source