Results 91 to 100 of about 64,777 (300)

A guide to neuromodulation in drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh, Irena Dolezawa, Manu Hegde, Lukas Imbach, Brian N. Lundstrom, Francesca Pizzo, Vikram R. Rao, Jaysingh Singh, Derek Southwell, Satsuke Watanabe, Birgit Frauscher   +10 more
wiley   +1 more source

Levetiracetam as an alternative to phenytoin for second-line emergency treatment of children with convulsive status epilepticus: the EcLiPSE RCT

Health Technology Assessment, 2020
Background: Convulsive status epilepticus is the most common neurological emergency in children. Its management is important to avoid or minimise neurological morbidity and death.
Richard E Appleton, Naomi EA Rainford, Carrol Gamble, Shrouk Messahel, Amy Humphreys, Helen Hickey, Kerry Woolfall, Louise Roper, Joanne Noblet, Elizabeth Lee, Sarah Potter, Paul Tate, Nadia Al Najjar, Anand Iyer, Vicki Evans, Mark D Lyttle   +15 more
doaj   +1 more source

Comparison of intranasal versus intravenous midazolam for management of status epilepticus in dogs : a multi‐center randomized parallel group clinical study [PDF]

, 2019
Background: The intranasal (IN) route for rapid drug administration in patients with brain disorders, including status epilepticus, has been investigated. Status epilepticus is an emergency, and the IN route offers a valuable alternative to other routes,
Bhatti, Sofie, Broeckx, Bart, Cappello, Rodolfo, Charalambous, Marios, Coates, Joan R, Corlazzoli, Daniele, Cozzi, Francesca, De Risio, Luisa, Erath, Johannes, Gallucci, Antonella, Gandini, Gualtiero, Hasegawa, Daisuke, Huenerfauth, Enrice, Musteata, Mihai, Pancotto, Theresa, Platt, Simon, Porcarelli, Laura, Rossmeisl, John H, Tipold, Andrea, Tirrito, Federica, Van Ham, Luc, Vanhaesebrouck, An, Volk, Holger A   +22 more
core   +1 more source

Can epilepsy be predicted after the first febrile seizure? Insights from machine learning of postictal EEG

Epileptic Disorders, EarlyView.
Abstract Objective Febrile seizures (FS) are the most common seizures in childhood, yet identifying children at risk of developing epilepsy after the first FS remains challenging. We aimed to evaluate the prognostic potential of machine learning (ML) algorithms applied to post‐febrile seizure electroencephalography (EEG) recordings.
Boran Şekeroğlu, Hüseyin Öztoprak, Özlem Yayıcı Köken, Hatice Demir, Mehpare Sarı Yanartaş, Deniz Yılmaz, Burçin Şanlıdağ, Ayşegül Neşe Çıtak Kurt   +7 more
wiley   +1 more source

Physiological reactivity to spontaneously occurring seizure activity in dogs with epilepsy and their carers [PDF]

, 2017
There is a complex bidirectional relationship between stress and epilepsy. Stressful stimuli and subsequent cortisol release act as a trigger for seizure activity in some individuals with epilepsy, and seizure activity itself may act as a stressor to the
Fowkes, R C, Packer, R M A, Volk, H A
core   +1 more source

Self‐limited neonatal epilepsy with 2q24.3 duplications: Case series and literature review

Epileptic Disorders, EarlyView.
Abstract Objective To clarify the phenotypic spectrum associated with duplications involving the 2q24.3 region, which includes a cluster of genes encoding sodium channel subunits (SCN1A, SCN2A, SCN3A, SCN7A, and SCN9A). Methods We reviewed our research database for patients with epilepsy and 2q24.3 duplication and performed thorough phenotyping.
Saba Al Rawahi, Kenneth A. Myers
wiley   +1 more source

Gut microbiota shifts and short‐chain fatty acids alterations in pediatric epilepsy patients on a Mediterranean ketogenic diet

Epileptic Disorders, EarlyView.
Abstract Objective The olive oil–based Mediterranean ketogenic diet (MedKD) may support patients with drug‐resistant epilepsy (DRE) or neurometabolic disorders by integrating ketogenic therapy with the cardiometabolic and neuroprotective advantages of the Mediterranean diet.
Sofia Zouganeli, Evdokia K. Mitsou, Mary Yannakoulia, Evangelia Intze, Konstantinos C. Mountzouris, Smaragdi Fessatou, Achilleas Attilakos, Adamantini Kyriacou, Argyrios Dinopoulos   +8 more
wiley   +1 more source

Status Epilepticus Type, Etiology, and Treatment: One-year Data

Archives of Epilepsy
Objective: This study aimed to review the demographic characteristics, type, and etiology of status epilepticus (SE) cases followed in our hospital for a period of 1 year and to reveal the factors affecting the prognosis of the patients.
Didar Çolakoğlu, Humay İsmayilzade, Berk Büke, Kadriye Ağan, İpek Midi   +4 more
doaj   +1 more source

Pediatric Absence Status Epilepticus: Prolonged Altered Mental Status in an 8-Year-Old Boy

Case Reports in Neurological Medicine, 2016
Absence status epilepticus is characterized by a prolonged state of impaired consciousness or altered sensorium with generalized electroencephalographic abnormalities.
Scott J. Adams, Melody Wong, Tahereh Haji, Shahmir Sohail, Salah Almubarak   +4 more
doaj   +1 more source

A Novel Long-term, Multi-Channel and Non-invasive Electrophysiology Platform for Zebrafish. [PDF]

, 2016
Zebrafish are a popular vertebrate model for human neurological disorders and drug discovery. Although fecundity, breeding convenience, genetic homology and optical transparency have been key advantages, laborious and invasive procedures are required for
Baraban, Scott C, Hong, SoonGweon, Lee, Luke P, Lee, Philip   +3 more
core   +1 more source