Results 91 to 100 of about 739,703 (314)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Preconception health behaviors associated with pregnancy planning status among Brazilian women

open access: yesRevista da Escola de Enfermagem da USP, 2016
OBJECTIVE The objective of this study is to assess preconception health behaviors among Brazilian women, and analyze the effect of pregnancy planning status in carrying out preconception measures.
Ana Luiza Vilela Borges   +4 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Re-writing political influence : the NSW (Australia) "rock star" planning reforms

open access: yes, 2018
The New South Wales (NSW) Environmental Planning and Assessment Act (EPAA) was promulgated in 1979 to simplify the planning process, to pay particular attention to ecological sustainability and to improve community consultation in planning matters.
Piracha, Awais (R13384)   +1 more
core  

Who is Being Saved Least by Family Planning Providers?A Study of Modern Contraceptive Use in Ghana,Tanzania and Zimbabwe [PDF]

open access: yes, 2004
\ud This study was conducted to identify the poorest and other vulnerable sub-groups being served least by family planning providers. The study was set in three countries in sub-Saharan Africa, namely, Ghana, Tanzania and Zimbabwe.
Madice, Nyovani, Clements , Steve
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Planning to be productive: the detailed retirement planning strategies of Australian pre-retirees [PDF]

open access: yes, 2012
Australia’s ageing population has resulted in a large cohort of Australians approaching retirement. Policy responses have recognised the significance of this, seeking to strengthen the labour force participation of older Australians to, in part, meet

core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Status of E.S.A. Plans [PDF]

open access: yesHighlights of Astronomy, 1977
After a symposium at Frascati, in October 1974, on Space Astrometry (E.S.R.O., SP-108, 1975) and a study on the mission definition (E.S.A., DP/PS (76) 11), a study of feasibility on the different proposed options will very probably be undertaken in October 1976 (Phase A).
openaire   +1 more source

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